Apolloscientific.co.uk

SAFETY DATA SHEET
Compilation date: 24/01/2007
Revision date: 25/02/2013
Revision No: 2
Section 1: Identification of the substance/mixture and of the company/undertaking
1.1. Product identifier
Product name: TETRACYCLINE HYDROCHLORIDE
CAS number: 64-75-5
EINECS number: 200-593-8
Product code: BIT0150
1.2. Relevant identified uses of the substance or mixture and uses advised against
1.3. Details of the supplier of the safety data sheet
Company name: Apollo Scientific Ltd
Tel: 0161 337 9971
Fax: 0161 336 6932
Email: [email protected]
1.4. Emergency telephone number
Section 2: Hazards identification
2.1. Classification of the substance or mixture
Classification under CHIP: Xi: R36/37/38
Classification under CLP: STOT SE 3: H335; Eye Irrit. 2: H319; Skin Irrit. 2: H315
Most important adverse effects: Irritating to eyes, respiratory system and skin.
2.2. Label elements
Label elements under CLP:
Hazard statements: H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Signal words: Warning
Hazard pictograms: GHS07: Exclamation mark
SAFETY DATA SHEET
Precautionary statements: P261: Avoid breathing dust.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
Label elements under CHIP:
Hazard symbols: Irritant.
Risk phrases: R36/37/38: Irritating to eyes, respiratory system and skin.
Safety phrases: S22: Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek S36/37/39: Wear suitable protective clothing, gloves and eye / face protection.
2.3. Other hazards
PBT: This substance is not identified as a PBT substance.
Section 3: Composition/information on ingredients
3.1. Substances
Chemical identity: TETRACYCLINE HYDROCHLORIDE
Section 4: First aid measures
4.1. Description of first aid measures
Skin contact: Remove all contaminated clothes and footwear immediately unless stuck to skin. Wash
immediately with plenty of soap and water. Eye contact: Bathe the eye with running water for 15 minutes. Consult a doctor.
Ingestion: Wash out mouth with water. Consult a doctor.
Inhalation: Remove casualty from exposure ensuring one's own safety whilst doing so. Consult a
4.2. Most important symptoms and effects, both acute and delayed
Skin contact: There may be irritation and redness at the site of contact.
Eye contact: There may be irritation and redness. The eyes may water profusely.
Ingestion: There may be soreness and redness of the mouth and throat.
Inhalation: There may be irritation of the throat with a feeling of tightness in the chest. Exposure may
4.3. Indication of any immediate medical attention and special treatment needed
Section 5: Fire-fighting measures
SAFETY DATA SHEET
5.1. Extinguishing media
Extinguishing media: Carbon dioxide, dry chemical powder, foam. Suitable extinguishing media for the
5.2. Special hazards arising from the substance or mixture
Exposure hazards: In combustion emits toxic fumes. Carbon oxides. Hydrogen chloride (HCl).
5.3. Advice for fire-fighters
Advice for fire-fighters: Wear self-contained breathing apparatus. Wear protective clothing to prevent contact
Section 6: Accidental release measures
6.1. Personal precautions, protective equipment and emergency procedures
Personal precautions: Refer to section 8 of SDS for personal protection details. If outside do not approach from
downwind. If outside keep bystanders upwind and away from danger point. Mark out the contaminated area with signs and prevent access to unauthorised personnel. Do not 6.2. Environmental precautions
Environmental precautions: Do not discharge into drains or rivers.
6.3. Methods and material for containment and cleaning up
Clean-up procedures: Transfer to a closable, labelled salvage container for disposal by an appropriate
6.4. Reference to other sections
Section 7: Handling and storage
7.1. Precautions for safe handling
Handling requirements: Avoid direct contact with the substance. Ensure there is sufficient ventilation of the area.
Do not handle in a confined space. Avoid the formation or spread of dust in the air. Only 7.2. Conditions for safe storage, including any incompatibilities
Storage conditions: Store in cool, well ventilated area. Keep container tightly closed. Store at -20 °C
Suitable packaging: Must only be kept in original packaging.
7.3. Specific end use(s)
Specific end use(s): No data available.
Section 8: Exposure controls/personal protection
8.1. Control parameters
Workplace exposure limits: Not applicable.
SAFETY DATA SHEET
8.2. Exposure controls
Engineering measures: Ensure there is sufficient ventilation of the area.
Respiratory protection: Self-contained breathing apparatus must be available in case of emergency. Respiratory
Hand protection: Protective gloves.
Eye protection: Safety glasses. Ensure eye bath is to hand.
Skin protection: Protective clothing.
Section 9: Physical and chemical properties
9.1. Information on basic physical and chemical properties
State: Powder
Oxidising: Non-oxidising (by EC criteria)
Solubility in water: Soluble
Melting point/range°C: 220-223
9.2. Other information
Other information: Not applicable.
Section 10: Stability and reactivity
10.1. Reactivity
Reactivity: Stable under recommended transport or storage conditions.
10.2. Chemical stability
Chemical stability: Stable under normal conditions.
10.3. Possibility of hazardous reactions
Hazardous reactions: Hazardous reactions will not occur under normal transport or storage conditions.
10.4. Conditions to avoid
Conditions to avoid: Heat.
10.5. Incompatible materials
Materials to avoid: Strong oxidising agents. Strong acids.
10.6. Hazardous decomposition products
Haz. decomp. products: In combustion emits toxic fumes of carbon dioxide / carbon monoxide. Nitrogen oxides
Section 11: Toxicological information
11.1. Information on toxicological effects
SAFETY DATA SHEET
Relevant hazards for substance:
Symptoms / routes of exposure
Skin contact: There may be irritation and redness at the site of contact.
Eye contact: There may be irritation and redness. The eyes may water profusely.
Ingestion: There may be soreness and redness of the mouth and throat.
Inhalation: There may be irritation of the throat with a feeling of tightness in the chest. Exposure may
Section 12: Ecological information
12.1. Toxicity
Ecotoxicity values: Not applicable.
12.2. Persistence and degradability
Persistence and degradability: No data available.
12.3. Bioaccumulative potential
Bioaccumulative potential: No data available.
12.4. Mobility in soil
Mobility: No data available.
12.5. Results of PBT and vPvB assessment
PBT identification: This substance is not identified as a PBT substance.
12.6. Other adverse effects
Other adverse effects: No data available.
Section 13: Disposal considerations
13.1. Waste treatment methods
Disposal operations: MATERIAL SHOULD BE DISPOSED OF IN ACCORDANCE WITH LOCAL, STATE AND
Disposal of packaging: Dispose of as special waste in compliance with local and national regulations Observe
all federal, state and local environmental regulations. NB: The user's attention is drawn to the possible existence of regional or national
Section 14: Transport information
SAFETY DATA SHEET
14.1. UN number
UN number: UNnone
14.2. UN proper shipping name
Shipping name: NOT CLASSIFIED AS DANGEROUS IN THE MEANING OF TRANSPORT REGULATIONS.
14.3. Transport hazard class(es)
14.4. Packing group
14.5. Environmental hazards
Environmentally hazardous: No
Marine pollutant: No
14.6. Special precautions for user
Section 15: Regulatory information
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
15.2. Chemical Safety Assessment
Chemical safety assessment: A chemical safety assessment has not been carried out for the substance or the mixture
Section 16: Other information
Other information
Other information: This safety data sheet is prepared in accordance with Commission Regulation (EU) No
* Data predicted using computational software. Toxtree - Toxic Hazard Estimation by decision tree approach. http://ecb.jrc.ec.europa.eu/qsar/qsar-tools/index.php? ~ Data predicted using computatioanl software ACD/ToxSuite v 2.95.1 Copyright 1994- 2009 ACD/labs, Copyright 2001-2009 Pharma Algorithms, Inc, Advanced Chemistry Development, Inc (ACD/Labs). http://www.acdlabs.com/products/pc_admet/tox/tox/ Phrases used in s.2 and 3: H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
R36/37/38: Irritating to eyes, respiratory system and skin.
Legal disclaimer: The material is intended for research purposes only and should be handled exclusively
by those who have been fully trained in safety, laboratory and chemical handling procedures. The above information is believed to be correct to the best of our knowledge. The above information is believed to be correct to the best of our knowledge at the date of its publication, but should not be considered to be all inclusive. It should be used only as a guide for safe handling, storage, transportation and disposal. We cannot guarantee that the hazards detailed in this document are the only hazards that SAFETY DATA SHEET
exist for this product. This is not a warranty and Apollo Scientific Ltd shall not be held liable for any damage resulting from handling or from contact with the above product.

Source: http://www.apolloscientific.co.uk/downloads/msds/BIT0150_msds.pdf