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Streck Tissue Fixative / Molecular Biology Fixative
Published Papers
Streck Laboratories, Inc.
7002 S. 109th Street La Vista, NE 68128
Phone: (800)843-0912 FAX: (402)333-4094
Replication of Herpes Simplex Virus Type 1 within Trigeminal Ganglia Is Required for High Frequency but Not High Viral
Genome Copy Number Latency
Richard L. Thompson1 and N.M.Sawtell2
Department of Molecular Genetics, Microbiology and Biochemistry, University of Cincinnati Medical Center, Cincinnati, Ohio
45267-05241, and Division of Infectious Diseases, Children’s Hospital Medical Center, Cincinnati, Ohio 49229-30392
Journal of Virology: 74(2) 965-974 January 2000
High Viral Load in the Cerebrospinal Fluid and Brain Correlates with Severity of Simian Immunodeficiency Virus
Encephalitis
M. Christine Zink1,2,3*, K. Suryanarayana4, J. Mankowski1,2, A. Shen1, M. Piatak, Jr.4, J.P. Spelman1, D.L. Carter1,2 , R.J. Adams1, J.D.
Lifson4, J.E.Clements1,2,5
Division of Comparative Medicine1, Department of Pathology2, and Department of Biochemistry and Molecular Biology5, Johns
Hopkins University School of Medicine, and Department of Molecular Microbiology and Immunology, Johns Hopkins School of
Hygiene and Public Health3, Baltimore, Maryland 21205, and Laboratory of Retroviral Pathogenesis, SAIC Frederick, National
Cancer Institute-Frederick Cancer Research and Development Center, Frederick, Maryland 217024
Journal of Virology: (73) 10480-10488 December 1999
Evaluation of Streck Tissue Fixative, a Nonformalin Fixative for Preservation of Stool Samples and Subsequent Parasitologic
Examination
Eva Nace, F. Steurer, Mark Eberhard
Division of Parasitic Diseases, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and
Human Services, Atlanta, Georgia 30341
Journal of Clinical Microbiology: (37) 4113-4119, December 1999
Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells
Z. Q. Zhang1, T. Schuler1, M. Zupancic1, S. Wietgrefe1, K. Staskus1, K. Reimann2, T.A. Reinhart3, M. Rogan1, W. Cavert1, C.J.
Miller4, R.S. Veazey2, D. Notermans5, S. Little6, S.A. Danner5, D.D. Richman6,10, D. Havlir6, J. Wong6,10, H.L.Jordan2, T.W.
Schacker7, P. Racz8, K. Tenner-Racz8, N.L. Letuin2, S. Wolinski9, A.T. Haase1*
Department of Microbiology, University of Minnesota Medical School Minneapolis, MN1; Division of Viral Pathogenesis, Beth
Israel Hospital, Harvard University, Boston, MA2; Department of Infectious Diseases and Microbiology, University of Pittsburgh,
Pittsburgh PA3; California Regional Primate Research Center, Davis California4; Division of Infectious Diseases, Tropical Medicine
and AIDS, Academic Hospital, University of Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands5; Department of
Pathology and Medicine, University of California-San Diego CA6; Department of Medicine, University of Minnesota Medical
School, Minneapolis, MN7; Bernhard-Nocht Institute for Tropical Medicine, Hamburg, Germany8; Division of Infectious Disease,
Northwestern University Medical School, Chicago, IL9; San Diego VA Health Care System, San Diego, CA10; To whom correspon-
dence should be addressed*
Science: 286(5443) 1353-1357 November 1999
Sezary T-Cell Activating Factor Is a Chlamydia pneumonia-Associated Protein
J. Todd Abrams1, E.C. Vonderheid1, S. Kolbe1, D.M. Appelt2, E.J. Arking2, B.J. Balin2
Departments of Dermatology1, and Pathology and Laboratory Medicine2, Medical College of Pennsylvania and Hahnemann
University, Philadelphia, PA 19102-1192
Clinical and Diagnostic Immunology: 6(6) 859-905, November 1999
Prevalence of Varicella-Zoster Virus DNA in Dissociated Human Trigeminal Ganglion Neurons on Nonneuronal Cells
James J. LaGuardia1, R.J.Cohrs1, and D.H. Gilden1,2*
Departments of Neurology1 and Microbiology2, University of Colorado Health Sciences Center, Denver Colorado 80262
Journal of Virology: 73(10) 8571-8577, October, 1999
Tissue Factor Pathway Inhibitor Attenuates Procoagulant Activity and Upregulation of Tissue Factor at the Site of Balloon-
Induced Arterial Injury in Pigs
James St. Pierre1, Lu-Ying Yang1, K. Tamirisa1, D. Scherrer1, P. De Ciechi2, P. Eisenberg, E. Tolunay2, D. Abendschien1
Washington University School of Medicine1 and Monsanto/Searle Research and Development2, St Louis, MO.
Arteriosclerosis Thrombosis and Vascular Disease: 19:2263-2268 September 1999
Synergistic Effects of Interferon g and Tumor Necrosis Factor a on T84 Cell Function
S.M. Fish1, R. Proujansky1,2, W.W. Reenstra1,2
Nemours Research Programmes of the Alfred I. DuPont Hospital for Children, Wilmington, Delaware, USA1, Department of
Pediatrics, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Gut: 45:191-198, August, 1999
Math1: An Essential Gene for the Generation of Inner Ear Hair Cells
N.A. Bermingham1,2, B. Hassan1,2, S.D. Price7, M.A. Vollrath5, N. Ben-Arie2, R.A. Eatock5,6, H.J. Bellen1,2,3,5, A. Lysakowski7, H.Y.
Zoghbi1,2,3,4,5.
Howard Hughes Medical Institute1, Department of Molecular and Human Genetics2, Department of Pediatrics3, Developmental
Biology Program4, Division of Neuroscience5, Bobby R. Alford Department of Otorhinolaryngology and Communicative Sciences6,
Baylor College of Medicine, Houston, TX 77030, USA: Department of Anatomy and Cell Biology, University of Illinois at Chicago,
Chicago, IL 60612, USA7.
Science: 284:1837-1841, June 11, 1999
10. Reversibility of the Pathological Changes in the Follicular Dendritic Cell Network with Treatment of HIV-1 Infection
Zhi-Qiang Zhang1, T. Schuler1, W. Cavert1, D. Notermans2, K. Genhard1, K. Henry4, D. Havlir5, H. Gunthard5, J. Wong5, S. Little5,
M. Feinberg7, M. Polis6, L. Schrager8, T. Schacker3, D. Richman5, L. Corey9, S. Danner2, A.T. Haase1
Departments of 1Microbiology and 3Medicine, University of Minnesota Medical School, Minneapolis, MN 55455; 2Division of
Infectious Diseases, Tropical Medicine, and AIDS and National AIDS Therapy Education Center Academic Medical Center,
University of Amsterdam, Netherlands, 4HIV Program, Regions Hospital, St. Paul, MN 55101; 5Departments of Medicine and
Pathology, University of California at San Diego, and San Diego Veterans Affairs Medical Center, 9500 Gilam Drive, La Jolla, CA
92093; 7Emory University School of Medicine, Atlanta, GA 30322; 6Laboratory of Immunoregulation, National Institute of Allergy
and Infectious Diseases/National Institutes of Health, Building 10, Room 11C103, 900 Rockville Pike, Bethesda MD 20892;, MD
20852; 8National Institute of Allergy and Infectious Diseases/National Institutes of Health, 6003 Executive Boulevard, Room 2C10,
Rockville, MD and 9Department of Laboratory Medicine and Microbiology, Pacific Medical Center, University of Washington,
Seattle WA 98144
Proceedings of the National Academy of Sciences: 96:5169-5172, April 1999
11. Characterization of a Novel Simian Immunodeficiency Virus (SIV) from L’Hoest Monkeys (Cercopithecus l’hoesti): Implica-
tions for the Origins of SIVmnd and Other Primate Lentiviruses
V. M. Hirsch1, B. Campell1, E. Bailes2, R. Goeken1, C. Brown1, W. Elkins3, M. Axthelm4, M. Murphey-Corb5 and P. M. Sharp2
Laboratory of Molecular Microbiology1 and Laboratory of Infectious Diseases3, National Institute of Allergy and Infectious
Diseases, NIH, Rockville, Maryland 20852; Division of Genetics, University of Nottingham, Queens Medical Center, Nottingham
NG7 ZUH, United Kingdom2, Division of Pathology, Oregon Regional Primate Research Center, Beaverton, Oregon 970064, and
Dept. of Microbiology, University of Pittsburgh, Pittsburgh, PA5.
Journal of Virology: 73(2):1036-1045, February 1999
12. Superoxide Mediates Cigarette Smoke-Induced Infiltration of Neutrophils into the Airways through Nuclear Factor-kB
Activation and IL-8 mRNA Expression in Guinea Pigs In Vitro
M. Nishikawa, N. Kakemizu, T. Ito, M. Kudo, T. Kaneko, M. Suzuki, N. Udaka, H. Ikeda, T. Okubo
First Department of Internal Medicine and Department of Pathology, Yokohama City University School of Medicine, Yokohama,
Japan
American Journal of Respiratory Cell and Molecular Biology: 20(2): 189-198, February 1999
13. RNA as a Target of Double-Stranded RNA-Mediated genetic Interference in Caenorhabditis elagans
M. K. Montgomery1,2, SiQun Xu1, A Fire1
Carnegie Institute of Washington, Department of Embryology, Baltimore, MD; Macalester College, Biology Department, St. Paul,
MN
Proceedings of the National Academy of Sciences: 95:15502-15507, December 1998
14. Urokinase and the Intestinal mucosa: Evidence for a Role in Epithelial Cell Turnover
P.R. Gibson1, I. Birchall2, O. Rosella1, V. Albert1, C.F. Finch1, D.H. Barkla3, G.P. Young1
Department of Medicine, The Royal Melbourne Hospital1; Department of Pathology, University of Melbourne2; Department of
Anatomy, Monash University, Victoria, Autralia3
Gut: 42: 656-663, November 1998
15. Pathogenesis of Simian Immunodeficiency Virus Pneumonia - An Immunopathological Response to Virus
J. Mankowski1, D. Carter1, J. Spelman1, M. Nealen1, K. Maughan1, L. Kirstein2, P. Didier3, R. Adams1, M. Murphy-Corb3, and M.C.
Zink1
Division of Comparative Medicine and Department of Pathology, Johns Hopkins University School of Medicine, Baltimore Mary-
land1; Departments of Epidemiology and Molecular Microbiology and Immunology, Johns Hopkins School of Public Health,
Baltimore Maryland2; and Tulane Regional Primate Research Center, Covington, Louisiana3
American Journal of Pathology: 153(4): 1123-1130, October 1998
16. Repertoire of Chemokine Receptor Expression in the Female Genital Tract - Implications for Human Immunodeficiency Virus
Transmission
B.K. Patterson1, A. Landay2, J. Andersson3, C. Brown4, H. Behbahani3, D. Jiyamapa1, Z. Burki1, D. Stanislawski1, M.A.
Czerniewski2, and P. Garcia1
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois1; Department of Immunol-
ogy/Microbiology, Rush Medical College, Chicago, Illinois2; Department of Immunology, Microbiology, Pathology and Infectious
Diseases, Karolinska Institute, Huddinge University Hospital, Huddinge, Sweden3; and Department of Medicine, Division of
Infectious Diseases, Northwestern University Medical School, Chicago, Illinois4
American Journal of Pathology:153(2) 481-490 August 1998
17. The Latent Herpes Simplex Virus Type 1 Genome Copy Number in Individual Neurons Is Virus Strain Specific and Corre-
lates with Reactivation
N.M. Sawtell1, D.K. Poon, C.S. Tansky, R.L. Thompson2
Division of Infectious Diseases, Children’s Hospital Medical Center, Cincinnati, Ohio 45229-30391, and Department of Molecular
Genetics, Microbiology and Biochemistry, University of Cincinnati Medical Center, Cincinnati, Ohio 45267-05242.
Journal of Virology: 72(7): 5343-5350, July 1998
18. Human Herpesvirus 8 in the Prostate Glands of Men with Koposi’s Sarcoma
C. Diamond, S. Brodie, J. Krieger, M. Huang, D. Koelle, K, Diem, D. Muthui and L. Corey
Departments of Medicine, Laboratory Medicine and Urology, University of Washington, and Program in Infectious Diseases, Fred
Hutchinson Cancer Research Center, Seattle, Washington
Journal of Virology: 72(7): 6223-6227, July 1998
19. In Vivo Distribution of Human Immunodeficiency Virus/Simian Immunodeficiency Virus Coreceptors: CXCR4, CCR3 and
CCR5
L. Zhang, T. He, A. Talal, G. Wang, S. Frankel and D. Ho
Aaron Diamond AIDS Research Center, The Rockefeller University, NY, NY 10016 and Division of Retrovirology, Walter Reed
Army Institute of Research, Rockville, Maryland 20850 and Department of Parasitic and Infectious Disease Pathology, Armed
Forces Institute of Pathology, Washington, D.C. 20306
Journal of Virology: 72(6): 5035-5045, June 1998
20. Gene Therapy for Non-Small Cell Lung Cancer: A Preliminary Report of a Phase 1 Trial of Adenoviral p53 Gene
Replacement
J.A. Roth, SG Swisher, JA Merritt, DD Lawrence, BL Kemp, CH Carrasco, AK El-Nagger, FV Fossella, BS Glisson, WK Hong, FR
Khurl, JM Kurie, JC Nesbitt, K Pisters, JB Putnum, DS Schrump, DM Shin, GL Walsh: Acknowledgments: N Yen, MD Anderson
Cancer Center, Houston TX (confirms STF usage for IHC and TUNEL applications)
Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX
Seminars in Oncology: 25(3): 33-37, June 1998
21. Alteration of Acrylic Bone Cement by Chemicals Used During Hard Tissue Specimen Processing
M. Harman1, S. Banks1, W.A. Hodge2
Orthopaedic Research Laboratory, Good Samaritan Medical Center, West Palm Beach, Florida1, Palm Beach Orthopaedic Institute,
West Palm Beach, Florida
Journal of Histotechnology: 21(2): 107-114, June 1998
22. Epizootic Hemorrhagic Disease: Analysis of Tissues by Amplification and In Situ Hybridization Reveals Widespread
Orbivirus Infection at Low Copy Numbers
S. Brodie, K. Bardsley, K. Diem, J. Mecham, S. Norelius, W. Wilson
Arthropod-Borne Animal Disease Research Laboratory, Agricultural Research Service, US Dept. of Agriculture, Laramie, Wyo-
ming: Virology Division/Retrovirology Laboratory, University of Washington School of Medicine, Seattle Washington; and Wyo-
ming Game and Fish Department, Sundance, Wyoming
Journal of Virology: 72(5): 3863-3871 May 1998
23. Kinetics of CD4+ T Cell Repopulation of Lymphoid Tissues After Treatment of HIV-1 Infection
Zhi-Qiang Zhang, D. W. Notermans, G. Sedgewick, W. Cavert, S. Wietgrefe, M. Zupancic, K. Gebhard, K. Henry, L. Boies, Z.
Chen, M. Jenkins, R. Mills, H. McDade, C. Goodwin, C. Schuwirth, S. Danner, A. T. Haase.
Departments of Microbiology, Cell Biology and Neuroanatomy, Medicine and Otolaryngology, University of Minnesota Medical
School, Minneapolis, MN 55455; Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; HIV
Program, St. Paul-Ramsey Medical Center, St. Paul, MN 55101; Gilead Sciences, Foster City, CA 94404; Glaxo-Welcome
Research and Development, Greenford, United Kingdom
Proceedings of the National Academy of Sciences: 95:1154-1159, February 1998
24. Cellular Localization of Latent Cytomegalovirus
A. Koffron, M. Hummel, B.K. Patterson, S. Yan, D.B. Kaufman, J.P. Fryer, F.P. Stuart, M.I. Abecassis.
Department of Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
Journal of Virology: 72(1): 95-103, January 1998
25. Hyperventilation-Induced Airway Injury and Vascular Leakage in Dogs: Effects of a1-adrenergic Agonists
N. Freed1, V. Taskar1, B. Schofield1, C. Omori2
Dept of Environmental Health Sciences, Division of Physiology, The Johns Hopkins University, Baltimore, Maryland1; First
Department of Internal Medicine, Nihon University School of Medicine, Tokyo Japan2.
J. Applied Physiology: 83(6): 1884-1889, December 1997
26. Comprehensive Quantification of Herpes Simplex Virus Latency at the Single-Cell Level
N.M. Sawtell
Division of Infectious Diseases, Children’s Hospital Medical Center, Cincinnati, Ohio
Journal of Virology: 71(7): 5423-5431, July 1997
27. Kinetics of Response in Lymphoid Tissues to Antiretroviral Therapy of HIV-1 Infection
[see comments] [published erratum appears in Science 1997 May 30;276(5317:1321].
Comments: Comment in Science 1997 May 9;276(5314):898-9, Comment in: Science 1997 Jun 13;276(5319):1629-30
Science: 276(5314): 960-4, May 1997
28. Latent Human Cytomegalovirus: a functional study
A.J. Koffron, B.K. Patterson, S. Yan, D.B. Kaufman, J.P. Fryer, F.P. Stuart, M.I. Abecassis.
Northwestern University Medical School, Department of Surgery, Chicago, Illinois 60611, USA
Transplantation Proceedings: 29(1-2):793-5, Feb-Mar 1997
29. New RNA in situ Fixative
B. Harfe1, A. Fire2
1The John Hopkins University Biology Graduate Program, The Carnegie Institution of Washington, 2 The Carnegie Institution of
Washington
Worm Breeders Gazette: 14(5): 22, February 1997
30. Effect of Furosemide on Hyperpnea-Induced Airway Obstruction, Injury and Microvascular Leakage
A.N. Freed, V. Taskar, B. Schofield, C. Omori
Dept of Environmental Health Sciences, Division of Physiology, The Johns Hopkins University, Baltimore, Maryland1; First
Department of Internal Medicine, Nihon University School of Medicine, Tokyo Japan2.
J. Applied Physiology: 81(6): 2461-2467, December 1996
31. Quantitative Image Analysis of HIV-1 Infection in Lymphoid Tissue.
A.T. Haase, K. Henry, M. Zupancic, G. Sedgewick, R.A. Faust, H. Melroe, W. Cavert, K. Gebhard, K. Staskus, Z.Q. Zhang, P.J.
Dailey, H.H. Balfour Jr, A. Erice, A.S. Perelson
Department of Microbiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Science: 274(5289): 985-9, November 1996
32. Detection of HIV-1 DNA in Cells and Tissues by Fluorescent in situ 5’-nuclease Assay (FISNA)
B.K. Patterson, D. Jiyamapa, E. Mayrand, B. Hoff, R. Abramson, P.M. Garcia
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois 60611, USA
Nucleic Acids Research: 24(18): 3656-8, September 1996
33. Elevated Levels of Plasminogen-activator Inhibitor Type 1 in Atherosclerotic Aorta
P.K. Shireman, W.J. McCarthy, W.H. Pearce, B.K. Patterson, V.P. Shively, M. Cipollone, N. Tamarina, E.N. Verrusio, H.C. Kwaan
Division of Vascular Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
Journal of Vascular Surgery: 23(5): 810-7; discussion 817-8, May 1996
34. Outpatient Biopsies of the Palatine Tonsil: Access to Lymphoid Tissue for Assessment of Human Immunodeficiency Virus
RNA Titers.
R.A. Faust, K. Henry, P. Dailey, H. Melroe, C. Sullivan, A. Erice, A.T. Haase, L.R. Boies Jr.
Department of Otolaryngology/Head and Neck Surgery, University of Minnesota Medical School, St. Paul, MN 55101, USA
Otolaryngology - Head and Neck Surgery: 114(4): 593-8, April 1996
35. In Situ Hybridization Histochemistry for Creatinine Kinase in the Brain
C.A. Barone, HT (ASCP), Senior Research Histologist, G.M. Hobson, Ph.D., Department of Clinical Science, Nemours Research
Programs Alfred I. du Pont Institute, Wilmington, Delaware USA
American Society of Clinical Pathologists - Tech Sample – Histotechnology, No. HT-2 (1996)
36. Cellular Targets of Infection and Route of Viral Dissemination After an Intravaginal Inoculation of Simian Immunodefi-
ciency Virus into Rhesus Macaques
A.I. Spira, P.A. Marx, B.K. Patterson, J. Mahoney, R.A. Koup, S.M. Wolinski, D.D. Ho
Aaron Diamond AIDS Research Center, New York University School of Medicine, New York 10016, USA
Journal of Experimental Medicine: 183(1): 215-25, Jan 1996
37. Infection of Macaca Nemestrina Brain with Human Immunodeficiency Virus Type 1
L.R. Frumkin, B.K. Patterson, J.B. Leverenz, M.B. Agy, S.M. Wolinsky, W.R. Morton, L. Corey
Department of Medicine, University of Washington School of Medicine, Seattle 98195, USA
Journal of General Virology: 76(Pt 10): 2467-76, October 1995
38. In Situ Localization and Quantification of Seventy-two-kilodalton Type IV Collagenase in Anneurysmal, Occlusive and
Normal Aorta.
W.D. McMillan, B.K. Patterson, R.R. Keen, W.H. Pearce
Department of Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
Journal of Vascular Surgery: 22(3): 295-305, September 1995
39. Determination of Radiation-Induced DNA Strand Breaks in Individual Cells by Non-radioactive Labeling of 3' OH Ends
R. Kodym and E. Horth
Clinic for Radiotherapy and Radiobiology, University of Vienna, Wahringer Gurtel 18-20, A-1090 Vienna, Australia
International Journal of Radiation Biology: 68(2): 133-139, April 1995
40. In Situ Localization and Quantification of mRNA for 92-kD type IV Collagenase and its Inhibitor in Aneurysmal, Occlusive
and Normal Aorta
W.D. McMillan, B.K. Patterson, R.R. Keen, V.P. Shively, M. Cipollone, W.H. Pearce
Department of Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
Arteriosclerosis, Thrombosis & Vascular Biology: 15(8): 1139-44, August 1995
41. In Situ Detection of HIV-1 DNA in Human Brain Tissue Using the GeneAmp In Situ PCR System 1000.
B.K. Patterson
Northwestern University Medical School, Chicago, Illinois, 60611 USA
Perkin-Elmer Technical Bulletin: March 1995
42. Genetic Differences between Blood- and Brain-Derived Viral Sequences from Human Immunodeficiency Virus Type-1-
infected Patients: Evidence of Conserved Elements in the V3 Region of the Envelope Protein of Brain Derived Sequences.
B.T. Korber, K.J. Kunstman, B.K. Patterson, M. Furtado, M.M. McEvilly, R. Levy, S.M. Wolinsky
Theoretical Biology and Biophysics, Theory Division, Los Alamos National Laboratory, New Mexico 87545, USA
Journal of Virology: 68(11): 7467-81, November 1994
43. Detection of HIV-1 DNA and Messenger RNA in Individual Cells by PCR-Driven In Situ Hybridization and Flow Cytometry
B.K. Patterson
Northwestern University Medical School, Chicago, Illinois 60611 USA
Science: 260:976-979, May 1993
44. Evaluation of Commercially Available Preservatives for Laboratory Detection of Helminths and Protozoa in Human Fecal Specimens.
S.M. Pietrzak-Johnston, H. Bishop, S. Wahlquist, H. Moura, N. De Oliveira Da Silva, S. Pereira Da Silva, P. Nguyen-Dinh
Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia and Hospital Universitário Pedro
Ernesto, Rio de Janeiro, Brazil
Journal of Clinical Microbiology: (00) 1959-1964, May 2000
If you would like additional information, please contact .
Streck Laboratories, Inc.
Anatomical and Molecular Pathology Division
1-800-843-0912
This publication list is provided for reference only. Streck makes no claim that any of the methods or procedures described indicateapproval for in vitro diagnostic use.

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