Robbert J. Verkes, MD, The Netherlands Cashier of the Board
Biography
Dr. Robbert J. Verkes is psychiatrist and clinical pharmacologist and holds a position as associate professor at the Department of Psychiatry at the Radboud University Medical Centre, Nijmegen, The Netherlands. He has been medical director of the Pompe Clinic for Forensic Psychiatry in Nijmegen. He currently is consultant in outpatient forensic psychiatric care. Dr. Verkes is chairman of the Dutch Association for Psychopharmacology and the section Biological Psychiatry of the Netherlands Association for Psychiatry (NVvP). He is member of various scientific advisory boards and has published about 100 peer-reviewed papers and book chapters. Currently, his group investigates the neurobiology and pharmacology of disorders of impulse and aggression regulation. Selected papers
Brazil I. A., Mars R.B., Bulten B.H., Buitelaar J.K., Verkes R.J., De Bruijn E.R. Neurophysiological correlates of the detection of own and other’s errors in individuals with psychopathy. (in press) Biol Psychiatry 2011 Lansbergen M.M., Dumont G.J., van Gerven J.M., Buitelaar J.K., Verkes R.J. Acute effects of MDMA (3,4-methylenedioxymethamphetamine) on EEG oscillations: alone and in combination with ethanol or THC (delta-9-tetrahydrocannabinol). Psychopharmacology. 2011; 213:745-56. van Marle H.J., Tendolkar I., Urner M., Verkes R.J., Fernández G., van Wingen G. Subchronic duloxetine administration alters the extended amygdala circuitry in healthy individuals. Neuroimage. 2011; 55: 825-31. van Wingen G., Rijpkema M., Franke B., van Eijndhoven P., Tendolkar I., Verkes R.J., Buitelaar J., Fernández G. The brain-derived neurotrophic factor Val66Met polymorphism affects memory formation and retrieval of biologically salient stimuli. Neuroimage. 2010; 50:1212-8. Schellekens A.F., Grootens K.P., Neef C., Movig K.L., Buitelaar J.K., Ellenbroek B., Verkes R.J. Effect of apomorphine on cognitive performance and sensorimotor gating in humans. Psychopharmacology. 2010; 207:559-69. van Wingen G., Mattern C., Verkes R.J., Buitelaar J., Fernández G.Testosterone reduces amygdala- orbitofrontal cortex coupling. Psychoneuroendocrinology. 2010; 35:105-13. Dumont G.J., Schoemaker R.C., Touw D.J., Sweep F.C., Buitelaar J.K., van Gerven J.M., Verkes R.J. Acute psychomotor effects of MDMA and ethanol (co-) administration over time in healthy volunteers. Journal of Psychopharmacology. 2010;24: 155-64. Dumont G.J., Kramers C., Sweep F.C., Willemsen J.J., Touw D.J., Schoemaker R.C., van Gerven J.M., Buitelaar J.K., Verkes R.J. Ethanol co-administration moderates 3,4-methylenedioxy- methamphetamine effects on human physiology. Journal of Psychopharmacology. 2010; 24:165-74. von Borries A.K., Brazil I.A., Bulten B.H., Buitelaar J.K., Verkes R.J., de Bruijn E.R. Neural correlates of error-related learning deficits in individuals with psychopathy. Psychological Medicine. 2010;40:1559-68. Schellekens A.F., de Bruijn E.R., van Lankveld C.A., Hulstijn W., Buitelaar J.K., de Jong C.A., Verkes R.J. Alcohol dependence and anxiety increase error-related brain activity. Addiction. 2010;105:1928- 34. van Eijndhoven P., van Wingen G., Fernández G., Rijpkema M., Verkes R.J., Buitelaar J., Tendolkar I. Amygdala responsivity related to memory of emotionally neutral stimuli constitutes a trait factor for depression. Neuroimage. 2011;54:1677-84.
van Wingen G.A., van Eijndhoven P., Cremers H.R., Tendolkar I., Verkes R.J., Buitelaar J.K., Fernández G. Neural state and trait bases of mood-incongruent memory formation and retrieval in first-episode major depression. J Psychiatr Res. 2010;44:527-34. van der Zwaluw C.S., Engels R.C., Vermulst A.A., Franke B., Buitelaar J., Verkes R.J., Scholte R.H. Interaction between dopamine D2 receptor genotype and parental rule-setting in adolescent alcohol use: evidence for a gene-parenting interaction. Molecular Psychiatry. 2010;15:727-35. Brazil IA, de Bruijn ERA, Bulten BH, von Borries AKL, van Lankveld JJDM, Buitelaar JK, Verkes RJ. Early and late components of error-monitoring in violent offenders with psychopathy. Biological Psychiatry. 2009;65:137-43. Dumont G., Sweep F., van der Steen R., Hermsen R., Donders A., Touw D., van Gerven J., Buitelaar J., Verkes R.J. Increased oxytocin concentrations and prosocial feelings in humans after ecstasy (3,4-methylenedioxymethamphetamine) administration. Social Neuroscience. 2009; 4: 359-66. Schellekens AF, van Oosterwijck AW, Ellenbroek B, de Jong CA, Buitelaar JK, Cools L, Verkes RJ. The dopamine agonist apomorphine differentially affects cognitive performance in alcohol dependent patients and healthy controls. European Neuropsychopharmacology. 2009;19:68-73. Grootens KP, van Luijtelaar G, Buitelaar JK, van der Laan A, Hummelen JW, Verkes RJ. Inhibition errors in borderline personality disorder with psychotic-like symptoms. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:267-73. de Bruijn ER, Grootens KP, Verkes RJ, Buchholz V, Hummelen JW, Hulstijn W. Neural correlates of impulsive responding in borderline personality disorder: ERP evidence for reduced action monitoring. J Psychiatr Res, 2006; 40:428-37. Grootens KP, Verkes RJ, Emerging evidence for effect of atypical antipsychotics in borderline personality disorder. Pharmacopsychiatry. 2005; 38: 20-23. Verkes RJ, Mast RC van der, Kerkhof AJFM, Fekkes D, Hengeveld MW, Tuyl JP, Van Kempen GMJ. Platelet serotonin, monoamine oxidase activity, and [3H]paroxetine binding related to impulsive suicide attempts and borderline personality disorder. Biological Psychiatry, 1998; 43:740-746. Verkes RJ, Mast RC van der, Hengeveld MW, Zwinderman AH, Tuyl JP, Van Kempen GMJ. Reduction by paroxetine of suicidal behavior in patients with repeated suicide attempts but not major depression. American Journal of Psychiatry, 1998; 155: 543-547 Verkes R.J., Pijl H., Meinders A.E., Van Kempen G.M.J., Borderline personality, impulsiveness and platelet monoamine measures in bulimia nervosa and recurrent suicidal behavior. Biological Psychiatry, 1996; 40: 173-180.
SUMMARY. This article reports on two research projects and argues that current medication management research and practice does not represent the complexity of community-based psychotropic treatment. Ethnographic findings are used to demonstrate that a social grid of man- agement exists to negotiate medication ‘effect’ interpretation. Anthropo- logical and semi-structured interview data are