Curriculum vitae Address:
Doeblinger Hauptstr.62/14, A-1190 Vienna, Austria, Tel.: 0676 760 6740
Current position:
Tenured Professor of Medicine,School of Medicine, University of Vienna, Department of Internal Medicine I, Division of Hematology and Hamostaseology, 1090 Vienna, Waehringer Guertel 18- 20, Austria. President of the Austrian Society of Oncological Rehabilitation and Psychooncology
Education/Training:
University of Vienna, Austria Fellowship
University of Vienna, Austria Board Exam 1995
University of Vienna, Austria Senior Attending Staff, on faculty 1995-present
University of Vienna, Austria Specialization 1997 Hematology/Oncology
University of Washington,USA Specialization 1998 Immunology/Oncology University of Vienna, Austria tenured Professor of Medicine 2002
Professional Experience:
Research Assistant University of Vienna, School of Medicine,
Post-doctoral Fellowship, Department of Laboratory Medicine,
Division of Molecular Biology, University of Vienna, Medical
Fellow, First Dept. of Internal Medicine, University of
Vienna. Research work on bcr-abl gene expression in CML
Faculty Appointment: Senior Attending Staff, Univ.of Vienna
Visiting Scientist, Senior Fellow, Division of Oncology,
Chair Hematology Research, Senior Scientist, Corixa Corp, Seattle, USA. 1.Development of WT1 cancer vaccine. 2. Decoding the genome of hematological malignancies.
2003–present Head hematology outpatient unit, Director Lymphoma, CLL,
Grants and Awards:
Fellowship Award of Excellence of the University of Vienna,
Fellowship Award of Excellence of the University of Vienna
Wilhelm Türk Award of the Austrian and German
Wilhelm Türk Award of the Austrian and German Society
Scientific Award for Pediatric Hematology and Oncology
of the Austrian Committee of the Children Cancer
Publications:
1. Over 100 patent publications 2. Full papers
Prognostic value of T-cell receptor gamma rearrangement in peripheral blood or bone marrow of patients with peripheral T-cell lymphomas. Leuk Lymphoma. 2008 Feb;49(2):237-46. Expression of MUM1/IRF4 mRNA as a prognostic marker in patients with multiple myeloma. Leukemia. 2007 Aug 9 Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia. Int J Cancer. 2007 Nov 1;121(9):1984-93. Autoimmune hemolytic anemias, Evans' syndromes, and pure red cell aplasia in non- Hodgkin lymphomas. Leuk Lymphoma. 2007 Jun;48(6):1139-49. Review. Clinical study on the effect of infrared radiation of a tiled stove on patients with hand osteoarthritis. Scand J Rheumatol. 2006 Nov-Dec;35(6):476-80. Upregulation of retinoic acid receptor-beta by the epidermal growth factor- receptor inhibitor PD153035 is not mediated by blockade of ErbB pathways. J Cell Physiol. 2007 Jun;211(3):803-15. Influence of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone on serologic parameters and clinical course in lymphoma patients with autoimmune diseases. Ann Oncol. 2007 Apr;18(4):647-51. Epub 2007 Jan 11. Assessment of disease dissemination in gastric compared with extragastric mucosa-associated lymphoid tissue lymphoma using extensive staging: a single-center experience. J Clin Oncol. 2006 Jul 1;24(19):3136-41. Epub 2006 Jun 12. Deregulated expression of fat and muscle genes in B-cell chronic lymphocytic leukemia with high lipoprotein lipase expression. Leukemia. 2006 Jun;20(6):1080-8. Phase II study of oxaliplatin for treatment of patients with mucosa-associated lymphoid tissue lymphoma. J Clin Oncol. 2005 Nov 20;23(33):8442-6.
Remission of pure red cell aplasia in T- cell receptor gammadelta-large granular lymphocyte leukemia after therapy with low-dose alemtuzumab. Leukemia. 2005 Nov;19(11):2005-8. No abstract available. Limited value of FLT3 mRNA expression in the bone marrow for prognosis and monitoring of patients with acute myeloid leukemia. Haematologica. 2005 May;90(5):695-6. Wilms' tumour gene 1 (WT1) in human neoplasia. Leukemia. 2005 Aug;19(8):1318-23. High expression of lipoprotein lipase in poor risk B-cell chronic lymphocytic leukemia. Leukemia. 2005 Jul;19(7):1216-23. An EGF receptor inhibitor induces RAR-beta expression in breast and ovarian cancer cells. Biochem Biophys Res Commun. 2005 Apr 22;329(4):1253-9. Gaiger A, Heintel D, Jäger U. Novel molecular diagnostic and therapeutic targets in chronic lymphocytic leukaemia. Eur J Clin Invest. 2004 Aug;34 Suppl 2:25-30. Review. High expression of activation-induced cytidine deaminase (AID) mRNA is associated with unmutated IGVH gene status and unfavourable cytogenetic aberrations in patients with chronic lymphocytic leukaemia. Leukemia. 2004 Apr;18(4):756-62. Diamond DL, Zhang Y, Gaiger A, Smithgall M, Vedvick TS, Carter DUse of ProteinChip array surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to identify thymosin beta-4, a differentially secreted protein from lymphoblastoid cell lines. J Am Soc Mass Spectrom. 2003 Jul;14(7):760-5. WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: therapeutic potential of WT1 targeted therapies. Leukemia. 2003 Jul;17(7):1301-12. Review. Gaiger AWT1-specific serum antibodies in patients with leukemia. Clin Cancer Res. 2001 Mar;7(3 Suppl):761s-765s. Gaiger AImmunity to WT1 in the animal model and in patients with acute myeloid leukemia. Blood. 2000 Aug 15;96(4):1480-9. Gaiger AWilms' tumour gene (wt1) expression at diagnosis has no prognostic relevance in childhood acute lymphoblastic leukaemia treated by an intensive chemotherapy protocol. Eur J Haematol. 1999 Aug;63(2):86-93. Immunophenotypic characterization of human bone marrow endosteal cells. Tissue Antigens. 1999 Jun;53(6):559-68.
Telomere length shortening is associated with disease evolution in chronic myelogenous leukemia. Am J Hematol. 1999 May;61(1):5-9. Gaiger ADetection of the WT1 transcript by RT-PCR in complete remission has no prognostic relevance in de novo acute myeloid leukemia. Leukemia. 1998 Dec;12(12):1886-94. Prognostic significance of WT1 gene expression at diagnosis in adult de novo acute myeloid leukemia. Leukemia. 1997 May;11(5):639-43. Amplification of mitochondrial DNA in acute myeloid leukaemia. Br J Haematol. 1996 Nov;95(2):426-31. Gaiger A,Increase of bcr-abl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progression. Blood. 1995 Sep 15;86(6):2371-8. Use of quantitative polymerase chain reaction to monitor residual disease in chronic myelogenous leukemia during treatment with interferon. Leukemia. 1995 Aug;9(8):1353-60. PCR-monitoring of minimal residual leukaemia after conventional chemotherapy and bone marrow transplantation in BCR-ABL-positive acute lymphoblastic leukaemia. Br J Haematol. 1995 Apr;89(4):937-41. Erratum in: Br J Haematol 1995 Jun;90(2):492. Absence of N-ras mutations in myeloid and lymphoid blast crisis of chronic myeloid leukemia. Cancer Res. 1994 Jul 15;54(14):3934-8. Gaiger AHLA class-I and -II antigens in chronic idiopathic autoimmune thrombocytopenia. Ann Hematol. 1994 Jun;68(6):299- 302. Gaiger A, Frequent detection of BCR-ABL specific mRNA in patients with chronic myeloid leukemia (CML) following allogeneic and syngeneic bone marrow transplantation (BMT). Leukemia. 1993 Nov;7(11):1766-72. Studies on oral contraceptive-induced changes in blood coagulation and fibrinolysis and the estrogen effect on endothelial cells. Ann Hematol. 1993 Jul;67(1):33-6. Early detection of relapse after bone marrow transplantation in patients with chronic myelogenous leukaemia. Lancet. 1993 Jan 30;341(8840):275-6. Monitoring of residual disease in chronic myelogenous leukemia by quantitative polymerase chain reaction. Leukemia. 1992 Jun;6(6):495-9.
[Problems of long-term therapy with anticoagulants] Acta Med Austriaca. 1992;19(1):21-4. Review. German. Pure red cell aplasia in a case of Ph negative BCR/ABL rearranged CML with t(12;14)(q23;p11). Cancer Genet Cytogenet. 1991 Oct 15;56(2):189-95. Gaiger ADetection of engraftment and mixed chimerism following bone marrow transplantation using PCR amplification of a highly variable region-variable number of tandem repeats (VNTR) in the von Willebrand factor gene. Ann Hematol. 1991 Oct;63(4):227-8. Gaiger A[Chronic myeloid leukemia] Wien Med Wochenschr. 1991;141(9-10):195-8. Review. German.
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