Pubblicazioni

--------------------------------------------------------Pubblicazioni dottorandi cicli XXI-XXIV
XXI CICLO

ROSARIA ARNONE
Savini I, Arnone R, Catani MV, Avigliano L. Origanum vulgare induces apoptosis
in human colon cancer caco2 cells. Nutr Cancer. 2009;61(3):381-9.
Savini I., Catani M.V., Arnone R., Rossi A., Frega G., Del Principe D., Avigliano L.
Translational control of the ascorbic acid transporter svct2 in human platelets. Free
Radical Biology & medicine 42 (2007) 608-616.
XXII CICLO
EFREM BERTINI

Didona B, Codispoti A, Bertini E, Rizzo WB, Carney G, Zambruno G, Dionisi-Vici C,
Paradisi M, Pedicelli C, Melino G, Terrinoni A. Novel and recurrent ALDH3A2
mutations in Italian patients with Sjogren-Larsson syndrome. J Hum Genet. 2007 Sep 28
[Epub ahead of print].
Bertini E, Oka T, Sudol M, Strano S, Blandino G. YAP: at the crossroad between
transformation and tumor suppression. Cell Cycle. 2009 Jan 1;8(1):49-57. Epub 2009
Jan 24. Review.
CHIARA DE SIMONE
Oddi S, Fezza F, Pasquariello N, D'Agostino A, Catanzaro G, De Simone C, Rapino C,
Finazzi-Agro’ A, Maccarrone M. Molecular identification of albumin and Hsp70 as
cytosolic anandamide-binding proteins. Chem Biol. 2009 Jun 26;16(6):624-32. Epub
2009 May 29
Fezza F, De Simone C, Amadio D, Maccarrone M. Fatty Acid Amide Hydrolase: A
Gate-Keeper of the Endocannabinoid System, Subcell Biochem. 2008; 49:101-132.
Fezza F, Oddi S, Di Tommaso M, De Simone C, Rapino C, Pasquariello N, Dainese E,
Finazzi-Agrò A, Maccarrone M. Characterization of biotin-anandamide, a novel tool for
the visualization of anandamide accumulation, J Lipid Res. 2008 Jun; 49 :1216-23.
Oddi S, Fezza F, Pasquariello N, De Simone C, Rapino C, Dainese E, Finazzi-Agrò A,
Maccarrone M. Evidence for the intracellular accumulation of anandamide in
adiposomes, Cell Mol Life Sci. 2008 Mar; 65 : 840-50.
Bari M,, Oddi S., De Simone C., Spagnolo P., Gasperi V, Battista N., Centonze D. and
Maccarrone M. Type-1 cannabinoid receptors colocalize with caveolin-1 in neuronal
cells. Neuropharmacology 2008 Jan; 54 : 45-50 [Epub ahead of print Jul 20].
Nucci C., Gasperi V., Tartaglione R., Cerulli A., Terrinoni A., Bari M,, De Simone C.,
Finazzi Agro` A., Morrone L. A., Corasaniti M. T., Bagetta G. and Maccarrone M.
--------------------------------------------------------Pubblicazioni dottorandi cicli XXI-XXIV Involvement of the Endocannabinoid System in Retinal Damage after High Intraocular
Pressure–Induced Ischemia in Rats, Invest Ophthalmol Vis Sci. 2007 Jul;48(7):2997-
3004.

ALESSANDRO GIAMBOI MIRAGLIA

Giamboi-Miraglia, A., Travagliane, S., Meschini, S., Falzano, L., Matarrese, P., Quaranta,
MG., Viora, M., Fiorentini, C., and Fabbri A. Cytotoxic necrotizing factor 1 prevents
apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2. Mol.
Biol. Cell 2007 18: 2735-2744.
Candi, E., Rufini, A., Terrinoni, A., Giamboi-Miraglia, A., Lena, AM., Mantovani, R.,
Knight, R., and Melino, G. DeltaNp63 regulates thymic development through enhanced
expression of FgfR2 and Jag2. Proc. Natl. Acad. Sci. 2007 104: 11999-112004.

Giamboi-Miraglia, A., Travagliane, S., Filippini, P., Fabbri, A., Fiorentini, C., and Falzano
L. A multinucleating Escherichia coli cytotoxic perturbs cell cycle in cultured epithelial cells.
Toxicol. In Vitro 2007 21: 235-239.
Falzano, L., Filippini, P., Travagliane, S., Giamboi-Miraglia, A. Fabbri, A., and Fiorentini,
C. Escherichia coli cytotoxic necrotizing factor 1 blocks cell cycle G /M transition in
uroepithelial cells. Infect. Immun. 2006 74: 3765-3772.

GIOVANNI PETRELLA
Ascenzi P, Petrella G, Coletta M. Ferricyanide-mediated oxidation of ferrous
nitrosylated sperm whale myoglobin involves the formation of the ferric nitrosylated
intermediate. Biochem Biophys Res Commun. 2007 Aug 10;359(4):871-6. Epub 2007
Jun 6.
De Sanctis G, Petrella G, Ciaccio C, Feis A, Smulevich G, Coletta M. A comparative
study on axial coordination and ligand binding in ferric mini myoglobin and horse heart
myoglobin. Biophys J. 2007 Sep 15;93(6):2135-42.

PIA RIVETTI

Rivetti di Val Cervo P, Tucci P, Majid A, Lena MA, Agostini M, Bernardini S, Candi
E, Cohen G, Nicotera P, Dyer MJ, Melino G. p73, miR106b, miR34a and Itch in chronic
lymphocytic leucemia. Blood. 2009 Jun 18;113(25):6498-9; author reply 6499-500.

Lena AM, Shalom-Feuerstein R, Rivetti di Val Cervo P, Aberdam D, Knight RA,
Melino G, Candi E. mir-203 represses “stemness” by repressing DeltaNp63. Cell Death
Differ. 2008 Jul;15(7):1187-95. Epub 2008 May 16.
Candi E, Cipollone R, Rivetti di Val Cervo P, Gonfloni S, Melino G, Knight R. p63 in
epithelial development. Cell Mol Life Sci. 2008 Oct;65(20):3126-33. Review.
--------------------------------------------------------Pubblicazioni dottorandi cicli XXI-XXIV Trandafir F, Hoogewijs D, Altieri F, Rivetti di Val Cervo P, Ramser K, Van Doorslaer
S, Vanfleteren JR, Moens L, Dewilde S. (2007) Neuroglobin and cytoglobin as potential
enzyme or substrate. Gene, 398(1-2): 103-113.

RENATO SABELLI
Sabelli R, Iorio E, De Martino A, Podo F, Ricci A, Viticchiè G, Rotilio G, Paci M,
Melino S. Rhodanese-thioredoxin system and allyl sulfur compounds. Implications in
apoptosis induction. FEBS J. 2008 Aug; 275(15):3884-99. Epub 2008 Jul 4.
XXIII CICLO

GIUSEPPE ASTARITA

Astarita G, Ahmed F, Piomelli D. Lipidomic analysis of biological samples by liquid
chromatography coupled to mass spectrometry. Methods Mol Biol. 2009;579:201-19.
Astarita G, Geaga J, Ahmed F, Piomelli D. Targeted lipidomics as a tool to investigate
endocannabinoid function. Int Rev Neurobiol. Elsevier Science 2009;85:35-55.
Nakahata Y, Sahar S, Astarita G, Kaluzova M, and Sassone-Corsi P. Circadian Control
of the NAD+ Salvage Pathway. Science. 2009 May 1;324(5927):654-7. Epub 2009 Mar
12.
Campolongo P, Roozendaal B, Trezza V, Cuomo V, Astarita G, Fu J, McGaugh JL,
and Piomelli D. The fat-induced satiety factor OEA enhances memory
consolidation. Proc Natl Acad Sci USA. 2009 May 12;106(19):8027-31. Epub 2009 Apr
27.
Guijarro A, Fu J, Astarita G, Piomelli D. CD36 gene deletion decreases
oleoylethanolamide levels in small intestine of free-feeding mice. Pharmacol Res. 2009
Sep 21. [Epub ahead of print].
Astarita G, Piomelli D. Lipidomic analysis of endocannabinoid metabolism in
biological samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jan 14.
[Epub ahead of print]
Astarita G, Ahmed F, Piomelli D. Identification of biosynthetic precursors for the
endocannabinoid anandamide in the rat brain. J Lipid Res. 2008 Jan;49(1):48-57. Epub
2007 Oct 23.
Potvin S, Kouassi E, Lipp O, Bouchard RH, Roy MA, Demers MF, Gendron A,
Astarita G, Piomelli D, Stip E. Endogenous cannabinoids in patients with
schizophrenia and substance use disorder during quetiapine therapy. J Psychopharmacol.
2008 May;22(3):262-9.
Fu J, Kim J, Oveisi F, Astarita G, Piomelli D. Targeted enhancement of
oleoylethanolamide production in proximal small intestine induces across-meal satiety
in rats. Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R45-50. Epub 2008
--------------------------------------------------------Pubblicazioni dottorandi cicli XXI-XXIV Apr 23.
Moise AM, Eisenstein SA, Astarita G, Piomelli D, Hohmann AG. An endocannabinoid
signaling system modulates anxiety-like behavior in male Syrian hamsters.
Psychopharmacology (Berl). 2008 Oct;200(3):333-46. Epub 2008 Jun 11.
Schwartz GJ, Fu J, Astarita G, Li X, Gaetani S, Campolongo P, Cuomo V, Piomelli D.
The lipid messenger OEA links dietary fat intake to satiety. Cell Metab. 2008
Oct;8(4):281-8.
Piomelli D, Astarita G, Rapaka R. A neuroscientist's guide to lipidomics. Nat Rev
Neurosci. 2007 Oct;8(10):743-54. Review.
Jung KM, Astarita G, Zhu C, Wallace M, Mackie K, Piomelli D. A key role for
diacylglycerol
endocannabinoid mobilization. Mol Pharmacol. 2007 Sep;72(3):612-21. Epub 2007 Jun
21.
Tarzia G, Antonietti F, Duranti A, Tontini A, Mor M, Rivara S, Traldi P, Astarita G,
King A, Clapper JR, Piomelli D. Identification of a bioactive impurity in a commercial
sample of 6-methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754). Ann Chim.
2007 Sep;97(9):887-94.
King AR, Duranti A, Tontini A, Rivara S, Rosengarth A, Clapper JR, Astarita G,
Geaga JA, Luecke H, Mor M, Tarzia G, Piomelli D. URB602 inhibits monoacylglycerol
lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.
Chem Biol. 2007 Dec;14(12):1357-65.
ANTONELLA BIONDO

Dharmapuri S., Aurisicchio L., Biondo A., Welsh N., Ciliberto G., La Monica N. Anti-
apoptotic siRNA as potent adjuvant of DNA vaccination in a mouse mammary tumor
model. Hum. Gene Ther. 2009 Feb 17.
Aurisicchio L., Peruzzi D., Conforti A., Dharmapuri S., Biondo A., Giampaoli S.,
Fridman A., Bagchi A., Winkelmann C.T., Gibson R., Kandimalla E.R., Agrawal S.,
Ciliberto G., La Monica N. Treatment of Mammary Carcinomas in HER-2 Transgenic
Mice through Combination of Genetic Vaccine and an Agonist of Toll-Like Receptor
9.Clin Cancer Res. 2009 Mar; 15(5):1575-84.
Conforti A., Peruzzi D., La Monica N., Ciliberto G., Biondo A., Giannetti
P.,Aurisicchio L. A novel model for evaluation and prediction of HLA-A2-restricted
CEA cancer vaccine responses. Journal of Immunotherapy, 2009 Sept; 32(7):744-54.

ELENA CAMPIONE

--------------------------------------------------------Pubblicazioni dottorandi cicli XXI-XXIV Caruso R, Botti E, Sarra M, Esposito M, Stolfi C, Diluvio L, Giustizieri ML,Pacciani V,
Mazzotta A, Campione E, Macdonald TT, Chimenti S, Pallone F, Costanzo A,
Monteleone G. Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis.
Nat Med. 2009 Sep;15(9):1013-5. Epub 2009 Aug 16.
Ambrogi V, Campione E, Mineo D, Paternò EJ, Pompeo E, Mineo TC. Bilateral
thoracoscopic T2 to T3 sympathectomy versus botulinum injection in palmar
hyperhidrosis. Ann Thorac Surg. 2009 Jul;88(1):238-45.
Campione E, Mazzotta A, Paternò EJ, Diluvio L, Prinz JC, Chimenti S. Effect of
calcipotriol on etanercept partial responder psoriasis vulgaris and psoriatic arthritis
patients. Acta Derm Venereol. 2009;89(3):288-91.
Orlandi A, Costantini S Campione E, Ferlosio A, Amantea A, Bianchi L, Chimenti S,
Spagnoli LG. Relation between animal-type melanoma and reduced nuclear expression
of glutathione S-transferase pi. Arch Dermatol. 2009 Jan;145(1):55-62.
Codispoti A, Colombo E, Zocchi L, Serra V, Pertusi G, Leigheb G, Tiberio R,
Bornacina G, Zuccoli R, Ramponi A, Campione E Melino G, Terrinoni A. Knuckle
pads, in an epidermal palmoplantar keratoderma patient with Keratin 9 R163W
transgrediens expression. Eur J Dermatol. 2009 Mar-Apr;19(2):114-8. Epub 2008 Dec
23.
Diluvio L, Campione E, Paternò EJ, Orlandi A, Terrinoni A, Chimenti S. Peculiar
clinical and dermoscopic remission pattern following imiquimod therapy of basal cell
carcinoma in seborrhoeic areas of the face. J Dermatolog Treat. 2009;20(2):124-9.
Campione E, Paternò EJ, Diluvio L, Orlandi A, Bianchi L, Chimenti S. Localized
morphea treated with imiquimod 5% and dermoscopic assessment of effectiveness. J
Dermatolog Treat. 2009;20(1):10-3.
Paternò EJ, Campione E, Diluvio L, Orlandi A, Chimenti S. Imiquimod for restoring
local immunity in a renal transplant patient with persistent keratoacanthoma. Dermatol
Online J. 2008 Mar 15;14(3):8.
Diluvio L, Campione E, Paterno EJ, Hagman JH, Anemona L, Orlandi A, Chimenti S.
Acute onset disseminated superficial porokeratosis heralding diffuse large B-cell
lymphoma. Eur J Dermatol. 2008 May-Jun;18(3):349-50. Epub 2008 May 13.
Campione E, Paternò EJ, Diluvio L, Bianchi L, Giorgetti G, Chimenti S. Combination
of low-dosage cyclosporine and topical pimecrolimus in severe atopic dermatitis with
chronic hepatitis B. Acta Derm Venereol. 2008;88(1):74-5.

ILDA D’ANNESSA

D'Annessa I., Chillemi G, Desideri A. Structural-dynamical properties of the
Deinococcus radiodurans topoisomerase IB in absence of DNA: correlation with the
human enzyme. J. Biomol. Struct. Dyn. 2009 Dec;27(3):307-18.
--------------------------------------------------------Pubblicazioni dottorandi cicli XXI-XXIV Fiorani P, Tesauro C, Mancini G, Chillemi G, D'Annessa I., Graziani G, Tentori L,
Muzi A, Desideri A. Evidence of the crucial role of the linker domain on the catalytic
activity of human topoisomerase I by experimental and simulative characterization of
the Lys681Ala mutant. Nucleic Acids Res. 2009 Sep 18. [Epub ahead of print]
Falconi M., Chillemi G., Di Marino D., D'Annessa I., Morozzo della Rocca B., Palmieri
L., Desideri A. Structural dynamics of the mitochondrial ADP/ATP carrier revealed by
molecular dynamics simulation studies. Proteins 2006. 65(3): 681-91.
Chillemi G., Fiorani P., Bruselles A., Castelli S., Campagna A., Sarra O., Tesauro C.,
Fiorentini M., Vassallo O., D'Annessa I., Santoleri S., Desideri A. Role of flexibility
and long range communication on the function of human topoisomerase I. Ital J
Biochem. 2007 56(2): 110-4. Review.
Losasso C, Cretaio E, Fiorani P, D'Annessa I, Chillemi G, Benedetti P. A single
mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and
drug resistance. Nucleic Acids Res. 2008 Oct;36(17):5635-44.
Chillemi G, D'Annessa I, Fiorani P, Losasso C, Benedetti P, Desideri A. Thr729 in
human topoisomerase I modulates anti-cancer drug resistance by altering protein domain
communications as suggested by molecular dynamics simulations. Nucleic Acids Res.
2008 Oct;36(17):5645-51.
ANTONELLA DE COLA

Bongiorno-Borbone L, De Cola A, Vernole P, Finos L, Barcaroli D, Knight RA, Melino
G, De Laurenzi V. FLASH and NPAT positive but not Coilin positive Cajal Bodies
correlate with cell ploidy. Cell Cycle. 2008 Aug;7(15):2357-67. Epub 2008 May 21.
De Cola A, Bongiorno-Borbone L, Barcaroli D, Knight RA, Di Ilio C, Melino G and
De Laurenzi V. FLASH degradation in response to UV-C results in Histone Locus
Bodies disruption and cell cycle arrest. Oncogene. 2009 In Press
RIDVAN NEPRAVISHTA

Melino S, Nepravishta R, Bellomaria A, Di Marco S, Paci M. Nucleic acid binding of
the RTN1-C C-terminal region: toward the functional role of a reticulon protein.
Biochemistry. 2009 Jan 20;48(2):242-53.

ANTONELLA PATRIARCA

Patriarca A, Eliseo T, Sinibaldi F, Piro MC, Melis R, Paci M, Cicero DO, Polticelli F,
Santucci R, Fiorucci L. ATP acts as a regulatory effector in modulating structural
transitions of cytochrome c: implications for apoptotic activity. Biochemistry. 2009 Apr
21;48(15):3279-87.
Sinibaldi F., Fiorucci L.,Patriarca A., Laceri R., Ferri T., Coletta M., and Santucci R.
--------------------------------------------------------Pubblicazioni dottorandi cicli XXI-XXIV Insights into cytochrome c-cardiolipin interaction. Role played by ionic strength,
Biochemestry 2008 47, 6928-6935.
DIEGO SBARDELLA

Gioia M, Monaco S, Van Den Steen PE, Sbardella D, Grasso G, Marini S, Overall
CM, Opdenakker G, Coletta M. The collagen binding domain of gelatinase A modulates
degradation of collagen IV by gelatinase B. J Mol Biol. 2009 Feb 20;386(2):419-34.
Epub 2008 Dec 14.
VALERIA SERRA

Codispoti A, Colombo E, Zocchi L, Serra V, Pertusi G, Leigheb G, Tiberio R,
Bornacina G, Zuccoli R, Ramponi A, Campione E, Melino G, Terrinoni A. Knuckle
pads, in an epidermal palmoplantar keratoderma patient with Keratin 9 R163W
transgrediens expression. Eur J Dermatol. 2009 Mar-Apr;19(2):114-8. Epub 2008 Dec
23. PubMed PMID: 19106041.
GRAZIA RAFFAELLA TUNDO

Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli
E, Coletta M. Somatostatin: a novel substrate and a modulator of insulin-degrading
enzyme activity. J Mol Biol. 2009 Feb 6;385(5):1556-67. Epub 2008 Nov 25.
XXIV CICLO

ALESSIA BELLOMARIA

Melino S, Nepravishta R, Bellomaria A, Di Marco S, Paci M. Nucleic acid binding of
the RTN1-C C-terminal region: toward the functional role of a reticulon protein.
Biochemistry. 2009 Jan 20;48(2):242-53.
RAFFAELE FABRINI

Fabrini R, De Luca A, Stella L, Mei G, Orioni B, Ciccone S, Federici G, Lo Bello M,
Ricci G. Monomer-Dimer Equilibrium in Glutathione Transferases: A Critical Re-
Examination. Biochemistry. 2009 Nov 3;48(43):10473-10482.
Liebau E, Dawood KF, Fabrini R, Fischer-Riepe L, Perbandt M, Stella L, Pedersen JZ,
Bocedi A, Petrarca P, Federici G, Ricci G. Tetramerization and cooperativity in
Plasmodium falciparum glutathione S-transferase are mediated by atypic loop 113-119.
J Biol Chem. 2009 Aug 14;284(33):22133-9. Epub 2009 Jun 16.

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