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acceptance: agreement by patient to a treatment routine they understand Accolate: brand name for zafirlukast, a leukotriene modifier (oral) acute: sudden adrenal insufficiency: inability of the body’s adrenal glands to produce an
adequate amount of cortisol, the hormone needed to respond to stress
adrenaline (epinephrine): a quick relief medicine, produced by the body and adrenergic: adrenaline-like medicine adverse: undesirable Aerobid: brand name for flunisolide, an inhaled steroid medicine, control er AeroChamber: brand of holding chamber Air Watch: airflow monitoring device with electronic link to the doctor airflow: the rate at which you can blow air out of your lungs albuterol: generic name of Proventil, Ventolin and ProAir; beta2-agonists, quick allergen: any substance that can induce an al ergy allergist: doctor who specializes in understanding and treating al ergies allergy: condition in which the body has an immune reaction to a substance that alveoli: air sacs located at the end of the tiniest airways ampule (ampoule): smal , sealed vial containing medicine in liquid form anaphylaxis: severe al ergic reaction throughout the body which can be fatal if
not treated immediately; commonly includes respiratory symptoms, itching,
antibody: protein that develops in the body in response to a foreign substance anticholinergic: type of inhaled quick relief medicine that acts through a antihistamine: generic name for medicine that blocks the actions of histamine, antiinflammatory: medicine that counteracts inflammation asthma: inflammatory disease of the airways characterized by airways that are
hyperresponsive and symptoms that can be reversed
Asthma Peak Flow Diary: an individual record of peak flow scores, medicines,
asthma signs, and triggers; helps in monitoring peak flow trends in people 5
asthma signs: physical indicators of asthma that can observed by another Asthma Signs Diary: an individual record of asthma signs scores, medicines,
and triggers that helps in monitoring the trends in asthma signs in children
asthma treatment zone: a range of peak flow scores or total scores of asthma
signs that cal s for fol owing a particular treatment plan
asymptomatic: without symptoms atopic: al ergic Atrovent: brand name for ipratropium bromide, an inhaled quick relief medicine attack: a dramatic term for an episode of asthma Azmacort: brand name for triamcinolone, an inhaled steroid medicine, control er beclomethasone: generic name for Vanceril, Beclovent, and QVAR, inhaled steroid medicines, control er Beclovent: brand name for beclomethasone, an inhaled steroid medicine,
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beta-blockers: medicines that block the action of beta-agonist medicines, and
responses of the sympathetic nervous system
beta2-agonist: a class of quick relief medicine b.i.d.: a dosing schedule cal ing for medicine to be taken twice a day blood concentration: amount of a substance in a given quantity of blood
expressed as weight per unit volume (e.g., mg/ml)
blow-by technique: a low-efficiency method for administering inhaled medicines breath-activated: method for triggering the release of medicine from a device by breathing cycle: total time it takes to breathe in and out once breathing rate: number of breaths per minute Brethaire: brand name for terbutaline, an inhaled beta2-agonist, quick relief Brethine: a brand name for terbutaline, an inhaled beta2-agonist, quick relief Bricanyl: a brand name for terbutaline, an inhaled beta2-agonist, quick relief bronchi: large air passages or airways bronchiolitis: inflammation of the smal est airways (bronchioles); caused by a bronchitis: inflammation of the large airways (bronchi) due to asthma, a virus or bronchoconstriction: narrowing of the airways caused by contraction of the
smooth muscles encircling them (same as bronchospasm)
bronchodilator: medicine that causes the airways to open bronchospasm: narrowing of the airways caused by contraction of the smooth
muscles encircling them (same as bronchoconstriction)
budesonide: generic name for Pulmicort, an inhaled steroid medicine, control er candidiasis: yeast infection in the mouth or vagina; same as moniliasis capillary: tiniest blood vessel cartilage: strong, flexible tissue that supports the large airways cc: abbreviation for cubic centimeter; equivalent to a mil iliter (ml) or 1/1000 of a
liter. This metric measurement is equal to 1/5 of a measuring teaspoon.
CDN: compressor driven nebulizer CFC: chlorofluorocarbon; propel ant used in most metered dose inhalers chemical mediator: class of chemical that plays a role in the asthma reaction; chronic: continuous or long-term cilia: tiny hairlike projections from the surface of the cel s that line the airway closed mouth technique: a method for inhaling medicine from an MDI; open- compliance: doing exactly what the doctor says, whether or not you understand compressor: machine that produces air under pressure compressor driven nebulizer (CDN): electric- or battery-powered device that
uses compressed air to create a medicine mist
consultation: ful review of a patient’s asthma history, physical exam, and other
information; leads to the creation of a written asthma management plan
controlled-release: same as long-acting, sustained-release, or slow-release;
applies to some theophylline and albuterol preparations
controller: medicine that prevents or reduces the frequency and severity of
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corticosteroid: another term for a steroid or cortisone-like medicine coughing asthma: form of asthma in which coughing is the only symptom croup: il ness usual y produced by a virus, in which the larynx and trachea are dander: scales of dead skin decongestant: a medicine that reduces congestion (swel ing) discard date: date when an MDI should be thrown away because it wil no Diskus: brand name for dry powder inhaler device diurnal variation: change within a day DPI: dry powder inhaler dry powder inhaler: device for inhaling asthma medicines in powder form;
depends on the force of inhalation to disperse medicine into the lungs
EasiVent: brand of holding chamber eczema: a skin rash, also known as atopic dermatitis effort monitor: part of a holding chamber which indicates the effort a person is electrostatic air precipitator: air cleaner eosinophils: white blood cel s involved in inflammation ephedrine: oral adrenergic medicine, bronchodilator; no longer commonly used epinephrine (adrenaline): a quick relief medicine, produced by the body and EpiPen: brand name for epinephrine for intramuscular use (injection); used to episode (flare): period of time when asthma signs or symptoms occur, peak flow
scores drop, breathing is changed, or additional asthma medicine is needed
exacerbation: worsening or new episode exercise induced asthma: a form of asthma in which exercise is the only trigger exhale: to breathe out expiration: act of breathing out extended-release: medicine preparation that acts over a longer period of time
than the standard preparation; also cal ed slow-release, sustained-release
E-Z Spacer: brand of holding chamber family practitioner: primary care physician who sees patients of al ages FEV1: forced expiratory volume in one second. This measurement of airflow is
done using a spirometer or simple FEV1 meter. It provides information about
the status of the large and smal airways
flare (episode): period of time when asthma signs or symptoms occur, peak flow
scores drop, breathing is changed, or additional asthma medicine is needed
Flovent: brand name for fluticasone, an inhaled steroid medicine available in flow monitor: part of a holding chamber which makes a sound if inhalation is too flunisolide: generic name for Aerobid, an inhaled steroid medicine, control er fluticasone: generic name for Flovent, an inhaled steroid medicine, control er gastroesophageal reflux: (also cal ed stomache acid reflux) backward flow of material from stomach to the esophagus; causes irritation which can lead to bronchospasm astham_terms_glossary.doc Created on 5/7/09 2:09 PM Last printed 5/7/09 3:03 PM Page 4 of 10 green zone: asthma treatment zone in which there are no symptoms and peak
flow is 80 to 100 percent of the personal best
growth retardation: slowing of rate at which height increases Gyrocap: capsule containing Slo-Phyllin, a slow-release theophylline hay fever: al ergic condition of the nose and eyes brought on mainly by ragweed or other pol en HEPAfilter: abbreviation for a “high-efficiency particulate air” filter; removes tiny HFA propellant: hydrofluoroalkane, a propel ant used in MDIs which does not
destroy ozone in the stratosphere (upper atmosphere)
high yellow zone: asthma treatment zone in which there are only mild
symptoms and peak flow is 65 to 80 percent of personal best
histamine: one of the chemical mediators of the asthma reaction hives: itchy swel ings of skin usual y due to al ergy holding chamber: inhalation device used with a metered dose inhaler that holds
the medicine mist to improve medicine effect
home care company: organization that provides many aspects of asthma care
in the home, including teaching, monitoring, and review of environment and
hyperresponsive: refers to airways that overreact to various asthma triggers hyperventilation: excessive rate and depth of breathing IAQ: indoor air quality I/E ratio: in/out ratio, or relative length of inhale compared to exhale IgE: immunoglobulin E, an antibody that reacts with an al ergen, initiating the immunotherapy: synonymous with al ergy shots, injection treatment, indication: reason to use indoor air quality (IAQ): overal healthfulness of the air inside a building inflammation: a response of the body to physical or chemical triggers; includes
swel ing due to movement of cel s, fluid, and chemicals into the area
inhalation device: apparatus for inhaling asthma medicine inhaled steroid: inhaled medicine that prevents inflammation in the airways and
reduces inflammation that already exists; the most commonly prescribed type
of control er medicine for people with persistent asthma
inhaler: also metered dose inhaler (MDI). Device that uses propel ant to create a
medicine mist that can be breathed into the airways
I/O ratio: in/out ratio, or relative length of inhale compared to exhale inspiration: act of breathing in InspirEase: brand of holding chamber inspiration-expiration ratio: see in/out (I/O) ratio intermittent flow director: a vent in the nebulizer tubing that, when covered, internist: primary care physician who sees adult patients intradermal: into the skin intravenous: into a vein intubation: placing a tube into the trachea to enable artificial breathing; can be a
lifesaving procedure during a severe asthma episode
ipratropium: generic name for Atrovent, an anticholinergic medicine, quick relief
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irritant: a nonal ergenic substance that may provoke a reaction in the airways kg: kilogram; 1,000 grams or 2.2 pounds levalbuterol: generic name for Xopenex, a beta2-agonist; quick relief medicine leukotriene: chemical mediator involved in the asthma reaction leukotriene modifier medicine: class of medicine that blocks the formation or
action of leukotrienes in the airways, thereby blocking part of the asthma
liter (L): metric measurement, slightly more than a quart liters/minute (L/min): a flow rate, applied to peak flow or oxygen delivery long-acting: synonymous with slow-release or sustained-release when referring
to a theophylline or beta2-agonist preparation
low yellow zone: asthma treatment zone in which symptoms are moderate and
peak flow is 50 to 65 percent of personal best
malingering: pretending to be il mask: a device that fits snugly over the nose and mouth; used to deliver inhaled mast cell: one of the cel types that contain chemicals which can produce the Maxair: brand name for pirbuterol, a beta2-agonist, quick relief medicine Maxair Autohaler: brand name for an MDI with a special “breath-activated”
release mechanism; contains pirbuterol (quick relief medicine)
mcg: microgram, 1/1,000,000 (one mil ionth) of a gram MDI: metered dose inhaler mean (average) peak flow score: the average peak flow score for people of a
certain height, expressed in liters per minute
median peak flow score: the peak flow score at which half of the people of a
specific height, gender and age wil be able to blow
mediator: a chemical that is the middleman or go-between in the asthma medicine retaining valve: valve in the exit port of a holding chamber which
holds medicine until a person begins to breathe in
Medrol: brand name of methylprednisolone, an oral steroid metabolize: to change chemical y or physical y in the body metered dose inhaler (MDI): device that creates medicine mist for inhalation by
using propel ant to expel liquid medicine
metaproterenol: generic name for beta2-agonist, quick relief medicine methylprednisolone: generic name for Medrol, oral steroid medicine methotrexate: immunosuppresive drug used to treat severe asthma that does
not respond to usual treatment; also used to treat cancer
micron: micrometer, 1/1,000,000 (one mil ionth) of a meter mg: mil igram, 1/1,000 (one thousandth) of a gram mite: tiny arachnid (spiderlike animal); skeleton and feces found in house dust ml: mil iliter, 1/1,000 of a liter; same as a cubic centimeter (cc) moniliasis (candidiasis): yeast infection in the mouth or vagina monitoring: keeping track of montelukast: generic name for Singulair, a leukotriene modifier medicine, mouthpiece: part of an asthma device which is put in the mouth
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mucus: protective and cleansing material produced by glands in the airways,
nose, sinuses, and elsewhere in the body
nebulizer (nebulizer cup): the smal plastic device that converts liquid medicine into a mist for inhalation normal (tidal) breath: usual breathing volume when no extra effort is made onset of action: time span from when a medicine is inhaled or swal owed until it open mouth technique: effective method for inhaling medicine from a metered osteoporosis: decrease in bone density causing increased bone fragility ozone: a form of oxygen (O3) that is a respiratory irritant; one component of ozone layer: layer of ozone in the upper atmosphere which encircles the Earth,
protecting the surface from harmful effects of cancer-causing ultraviolet light
palate: roof of mouth peak expiratory flow rate (PEFR): speed at which air exits the lungs when you
give your fastest blast (a fraction of a second); also known as peak flow
peak flow meter: a device used to measure peak expiratory flow rate peak flow score: the best of three attempts blown on the peak flow meter, peak flow zone: one of the treatment zones of asthma management as defined Pediapred: brand name of prednisolone, an oral steroid pediatrician: primary care physician for children persistent asthma: condition in which a person experiences asthma symptoms
two or more times a week (when taking no asthma medicine)
personal best peak flow score: highest peak flow score that an individual has
blown on two separate days when the airways are completely clear and
pirbuterol: generic name for Maxair; beta2-agonist, quick relief medicine pollen: potent al ergen shed during a plant’s flowering season pollutant: impurity or substance that contaminates the air post bronchodilator: airflow that occurs after inhaling a quick relief medicine ppm: parts per mil ion. Number of molecules of a particular substance (e.g., a
pol utant) found in a mil ion molecules of air, water, etc.
prebronchodilator: rate of airflow that occurs before inhaling a quick relief prednisone: generic name of oral steroid medicine; many brand names prednisolone: generic name for Prelone and Pediapred; oral steroid medicine Prelone: a brand name for prednisolone, an oral steroid prick test: type of skin test for al ergy Proventil HFA: brand name for albuterol; beta2-agonist, quick relief medicine Proventil Repetabs: brand name for long-acting albuterol preparation; oral puffer: another word for inhaler or MDI Pulmicort Turbuhaler: brand name for a dry powder inhaler containing pulmonary function test: a test or series of tests used to measure various pulmonologist: doctor specializing in the care of people with lung diseases astham_terms_glossary.doc Created on 5/7/09 2:09 PM Last printed 5/7/09 3:03 PM Page 7 of 10 q.i.d.: four times per day dosing schedule quick relief medicine: inhaled medicine that acts to open constricted airways
within minutes (e.g., inhaled beta2-agonists)
QVAR: brand name for beclomethasone, an inhaled steroid medicine; control er rast: radioimmunosorbent test, an al ergy test that measures IgE (antibody) to a rad: abbreviation for reactive airway disease, a name for asthma red zone: asthma treatment zone in which symptoms are severe and peak flow
is less than 50 percent of personal best; requires immediate treatment
relative humidity: amount of water in the air compared to the total amount of
water the air can hold at a given temperature
rescue medicine: quick relief medicine respiratory therapist: health professional who provides assessment, treatment,
and education for people with lung disease
respirable range: size of particles that can be inhaled into the smal airways (1 retraction: “sucking in” of the skin between the ribs or above and below the ROAD: reversible obstructive airway disease, a term that is sometimes used to runout time: length of time it takes for the effect of a medicine to disappear after
the last dose; may be minutes, hours, or days
salmeterol: generic name for Serevent; inhaled long-acting beta2-agonist, sensitization: process of becoming sensitized to an al ergen sensitizer: al ergen or irritant that primes the asthma reaction Serevent: brand name for salmeterol, control er serum: the liquid portion of the blood serum level: the amount of medicine in a quantity of serum shake test: shaking the MDI canister, an unreliable method for determining
whether the MDI can deliver a ful puff of medicine
side effect: undesired or adverse effect of medicine sign: an effect that can be seen or heard by an observer Singulair: brand name for montelukast, a leukotriene modifier medicine, sinuses: one of the eight bone-enclosed cavities surrounding the nose sinusitis: inflammation of one or more paranasal (around the nose) sinuses small airways: airways less than 2 mm in diameter; bronchioles Space Chamber: brand of holding chamber spacer: device used with an MDI to improve effectiveness; also known as Spinhaler: brand name for dry-powder device containing cromolyn; control er
medicine; no longer available in the U.S.
spirometer: device used in a doctor’s office to measure various components of spirometry: the act of using a spirometer step down: method for bringing asthma under control quickly, then gradual y
decreasing medicines to the lowest effective dose
steroid burst: a short treatment with oral steroids, usual y lasting for seven days
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steroid: type of hormone produced by the adrenal cortex which has
anti nflammatory effects. Also, medicine similar to this hormone that is given by
inhalation or oral y to help control asthma
subcutaneous: under the skin sustained-release: synonymous with long-acting or extended-release; refers to
theophylline and beta2-agonist preparations
sympathomimetic: produces the same effect as epinephrine injection or
stimulation of sympathetic nervous system
symptoms: any effect on your body that you can feel that is different from usual;
for example, a tight chest or shortness of breath
terbutaline: generic name for Brethaire, Brethine, Bricanyl; beta2-agonist, quick Theo-24: brand name for a long-acting theophylline preparation, control er, oral Theo-Dur: brand name for a long-acting theophylline preparation, control er, oral theophylline: slow-acting brochodilator medicine; control er, oral tidal breathing: normal, relaxed breathing toxicity: quality of being poisonous; the adverse effect(s) of a medicine triamcinolone: generic name for Azmacort, inhaled steroid preparation trigger: instigator; precipitating factor in causing airway inflammation and asthma twitchy: overreactive, hyperresponsive; used in reference to airways ultrasonic: sound waves above the range that humans can hear; can cause a ultrasonic nebulizer: device that uses sound waves to create medicine mist;
usual y smal , light, and portable. It should not be used to deliver a suspension,
unit dose: medicine in liquid or pil form that is packaged in individual doses Uni-Dur: brand name for a long-acting theophylline preparation, control er, oral Uni-Phyl: brand name for a long-acting theophylline preparation, control er, oral USN: ultrasonic nebulizer valve: device that regulates the flow of air or other substance Vanceril: brand name for beclomethasone; an inhaled steroid medicine, vent: tube that can be uncovered to interrupt the flow of air into a compressor Ventolin: brand name for albuterol, a beta2-agonist, quick relief medicine voice box: larynx, part of the upper airways which lies between the throat and wheeze: high-pitched whistling that occurs when air flows through narrowed airways white blood cells: cel s whose main function is to defend the body from bacteria Windmill Trainer: a feedback device for people who use a MiniWright peak flow
meter to improve their ability to blow peak flow
workup: evaluation of a patient Xopenex: brand name for levalbuterol, a beta2-agonist, quick relief medicine
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zafirlukast: generic name for Accolate, a leukotriene modifier; control er zone borders: limits of the asthma treatment zones as defined by peak flow or zileuton: generic name for Zyflo, a leukotriene modifier medicine; control er Zyflo: brand name for the zileuton, a leukotriene modifier medicine; control er
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November 2009 Research News • Fermentative maceration is an important step in the production of red wines, during which phenolic and volatile compounds are extracted from the grape solids, particularly from the skins. These compounds influence the quality and typicality of red wines. Many maceration techniques have been studied with the goal of enhancing the extraction of t