Fiche de pr_sentation individuelle
Present address UPCM CR7 Université Pierre et Marie Curie, INSERM U1135, CNRS ERL 8255,
Pitié-Salpêtrière, 91 Bd de l’Hôpital, 75013 Paris, France.
Tel: +33 6 85 31 06 49 e-ma
Positions since 2000
2000-2004
Senior Researcher, then DR2 CNRS (URA 2581), in the laboratory of Dr.
Pierre Druilhe, Unité de Parasitologie Biomédicale, Institut Pasteur, 25 Rue Du Dr. Roux, 75724 Paris Cedex 15, France.
2004-2008
Head of USM0307 (IFR101), Unité de Parasitologie Comparée et Modèles
Expérimentaux, Muséum National d'Histoire, CP52, 61 Rue Buffon, 75231 Paris Cedex 5, France.
2008-2013
Senior Scientist at the UPMC/INSERM UMR S 945 (previously UMR S 911)
“
Immuno-Biologie Cellulaire et Moléculaire des Infections Parasitaires”, Université Pierre et Marie Curie (Paris VI), Centre Hospitalo-Universitaire Pitié-Salpêtrière, 91 Boulevard de l’Hôpital-75643 Paris Cedex 13, France.
(2008-2011) Visiting Senior Research Fellow, Laboratory of Molecular and Cellular Parasitology,
Department of Microbiology, National University of Singapore, Singapore.
(2008-2011) Visiting Senior Researcher, Laboratory of Malaria Immunobiology, Singapore
Immunology Network, A*STAR - Biopolis, Singapore.
2014- Co-Head of the CIMI’s Team 6 “Malaria: identification and pre-clinical validation of novel
therapeutics”UPCM CR7 Université Pierre et Marie Curie, INSERM U1135, CNRS ERL 8255, Pitié-Salpêtrière, 91 Bd de l’Hôpital, 75013 Paris, France.
Selected Publications (past 10 years) H factor: 41
1. Belnoue E, Costa FTM, Frankenberg T, Vigário AM, Voza T, Leroy N, Rodrigues MM, Landau I,
Snounou G, & Rénia L (2004) Protective T cell immunity against malaria liver stage after
vaccination with live sporozoites under chloroquine treatment
. Journal of Immunology 172, 2487-
295.
2. Imwong M, Pukrittayakamee S, Grüner AC, Rénia L, Letourneur F, Looareesuwan S, White NJ, &
Snounou G (2005) Practical PCR genotyping protocols for
Plasmodium vivax using
Pvcs and
Pvmsp1. Malaria Journal 4, 20.
3. Grüner AC, Hez-Deroubaix S,
Snounou G, Hall N, Bouchier C, Letourneur F, Landau I, & Druilhe
P (2005) Insights into the
P. y. yoelii hepatic stage transcriptome reveal complex transcriptional
patterns
. Molecular and Biochemical Parasitology 142, 184-192.
4. Voza T, Vigário AM, Belnoue E, Grüner AC, Deschemin J-C, Kayibanda M, Delmas F, Janse CJ,
Franke-Fayard B, Waters AP, Landau I,
Snounou G, & Rénia L (2005) Species-specific inhibition
of cerebral malaria in mice coinfected with
Plasmodium spp
. Infection and Immunity 73, 4777-
4786.
5. Carraz M, Jossang, A, Franetich, JF, Siau A, Ciceron L. Hannoun L, Sauerwein R, Frappier F,
Rasoanaivo P,
Snounou G & Mazier D (2006) A plant-derived morphinan as a novel lead
compound active against malaria liver stages.
PLoS Medicine 3, e513.
6. Imwong M,
Snounou G, Pukrittayakamee S, Tanomsing N, Kim JR, Nandy A, Guthmann JP,
Nosten F, Carlton J, Looareesuwan S, Nair S, Sudimack D, Day NP, Anderson TJ & White NJ
(2007) Relapses of
Plasmodium vivax infection usually result from activation of heterologous
hypnozoites.
Journal of Infectious Diseases 7, 927-933.
7. Yamauchi LM, Coppi A,
Snounou G & Sinnis P (2007)
Plasmodium sporozoites trickle out of the
injection site.
Cellular Microbiology 9, 1215-1222.
8. Grüner AC, Mauduit M, Tewari R, Romero JF, Depinay N, Kayibanda M, Lallemand E, Chavatte
JC, Crisanti A, Sinnis P, Mazier D, Corradin G,
Snounou G & Rénia L (2007) Sterile protection
against malaria is independent of immune responses to the circumsporozoite protein.
PLoS ONE 2,
e1371.
9. Roestenberg M, McCall M, Hopman J, Wiersma J, Luty AJF, Van Gemert G-J, Van de Vegte-
Bolmer M, Van Schaijk B, Teelen K, Arens T, Spaarman L, De Mast Q, Roeffen W,
Snounou G,
Rénia L, Van der Ven A, Hermsen CC & Sauerwein R (2009) Protection against a malaria
challenge by sporozoite inoculation.
New England Journal of Medicine 361, 468-477.
10. Mazier D, Rénia L &
Snounou G (2009) A pre-emptive strike against malaria's stealthy hepatic
forms.
Nature Reviews. Drug Discovery 8, 854-64.
11. Krief S, Escalante AA, Pacheco MA, Mugisha L, André C, Halbwax M, Fischer A, Krief J-M,
Kasenene JM, Crandfield M, Cornejo OE, Chavatte J-M, Lin C, Letourneur F, Grüner AC,
McCutchan TF, Rénia L &
Snounou G (2010) On the diversity of malaria parasites in African apes
and the origin of
Plasmodium falciparum from bonobos.
PLoS Pathogens 6, e1000765.
12. Sutherland CJ, Tanomsing N, Nolder D, Oguike M, Jennison C, Pukrittayakamee S, Dolecek C,
Tran Tinh Hien, Do Rosário VE, Arez AP, Pinto J, Michon P, Escalante AA, Nosten F, Burke M,
Lee R, Blaze M, Otto TD, Barnwell JW, Pain A, Williams J, White NJ, Day NPJ,
Snounou G,
Lockhart PJ, Chiodini PL, Imwong M & Polley SD (2010) Two nonrecombining sympatric forms
of the human malaria parasite
Plasmodium ovale occur globally.
Journal of Infectious Diseases 201, 1544-1550.
13. Carvalho BO, Lopes SCP, Nogueira PA, Orlandi PP, Bargieri DY, Blanco YC, Mamoni R, Leite
JA, Rodrigues MM, Soares IS, Oliveira TR, Wunderlich G, Lacerda MVG, Del Portillo HA,
Araújo MOG, Russell B, Suwanarusk R,
Snounou G, Rénia L & Costa FTM (2010) On the
cytoadhesion of
Plasmodium vivax-infected erythrocytes.
Journal of Infectious Diseases 202, 638-
647.
14. Dembélé L, Gego A, Zeeman A-M, Franetich J-F, Silvie O, Rametti A, Le Grand R, Dereuddre-
Bosquet N, Sauerwein R, van Gemert G-J, Vaillant J-C, Thomas AW,
Snounou G, Kocken CHM
& Mazier D (2011) Towards an
in vitro model of
Plasmodium hypnozoites suitable for drug
discovery.
PLoS ONE 6, e18162.
15. Russell B, Suwanarusk R, Borlon C, Costa FTM, Chu CS, Rijken MJ, Sriprawat K, Warter L, Koh
EGL, Malleret B, Colin Y, Bertrand O, Adams JH, D'Alessandro U,
Snounou G, Nosten F &
Rénia L (2011) A reliable
ex vivo invasion assay of human reticulocytes by
Plasmodium vivax.
Blood 118, e74-e81.
16. Obeid M, Franetich J-F, Lorthiois A, Gego A, Grüner AC, Tefit M, Boucheix C,
Snounou G &
Mazier D (2013) Skin-draining lymph node priming is sufficient to induce sterile immunity against
pre-erythrocytic malaria.
EMBO Molecular Medicine 5, 250-263.
17.
Snounou G & Pérignon J-L (2013) Malariotherapy - Insanity at the service of malariology.
Advances in Parasitology 81, 223-255.
18. Dembélé L, Franetich JF, Lorthiois A, Gego A, Zeeman AM, Kocken CH, Le Grand R, Dereuddre-
Bosquet N, Sauerwein R, van Gemert GJ, Vaillant JC, Hannoun L, Fuchter MJ, Malmquist NA,
Scherf A,
Snounou G, Mazier D. (2014) Persistence and activation of malaria hypnozoites in long-
term primary hepatocyte cultures.
Nature Medicine 2014, Feb 9.
Source: http://www.cimi-paris-malaria-team12.net/CV_Georges_Snounou.pdf
Meer over ontstaan en werking van Ginseng extractum Panax Ginseng is de wetenschappelijke naam voor een plant uit de familie waartoe ook onze klimop behoort. Panax vinden we terug in 'panacee' (middel voor alle kwaaltjes), Ginseng is afgeleid van het Chinese 'ren shen', wat zoiets als man-wortel betekent, verwijzend naar de menselijke vorm van de Ginsengwortel. In Korea was de jaarlijkse zoekt
Prevention of Intravascular Catheter Infections –Insights and Prospects for Hemodialysis Catheters L.A. Mermel Division of Infectious Diseases, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island, USAHemodialysis catheters have become an invaluable device inIn a prospective, randomized trial, maximal barrier precau-management of patients with acute rena