MEDICATION CHART Page 1 MEDICATION TREATMENT POSSIBLE SIDE EFFECTS FIRST LINE DRUGS Phenytoin
Nausea, vomiting, constipation, poor appetite,
headaches, dizziness, drowsiness, muscle twitches,
sleeplessness, swollen tender gums, excess hair
growth, coarsening of facial features, blurred or
double vision, slurred speech, unsteadiness on thefeet, jerky movements of eyes, confusion. (Veryrare is joint swelling, pain and muscle aches). Sodium Valproate
Nausea, vomiting, stomach upset, diarrhoea,
increased appetite, weight gain, fluid retention,
sweating, excessive thirst and urination, bed
wetting, hair loss, skin rash. (Very rare is liverdamage, inflammation of pancreas, decreasednumber of blood platelets). Carbamazepine
Drowsiness, dizziness, unsteadiness, ringing in
the ears, increased sensitivity to sound, blurred
or double vision, pins and needles or numbnessin the extremities, nausea, vomiting, abdominalpains, poor appetite, diarrhoea, constipation. gastric irritation, frequent urination, allergicskin reaction. (Very rare is liver inflammation,impaired kidney function). Ethosuximide
Effective against absence seizures only.
Nausea, vomiting, stomach upset, poor appetite.
headache, dizziness, drowsiness, fatigue, poor
concentration, hyperactivity, irritability, hiccups,swollen tender gums, excess hair growth. SECOND LINE DRUGS continues over page Lamotrigine
Dizziness, headache, double vision, unsteady
gait or poor balance, drowsiness, blurred vision,
nausea, vomiting, weakness or fatigue.
Rash (more likely if person already taking Epilim) -should be reported to doctor immediately.
Lower doses should be used if on Epilim. Gabapentin
Drowsiness, sedation, dizziness, ataxia, fatigue,
nausea, vomiting, blurred vision, weight gain,
unsteady gait, involuntary movement of eyeballs,
memory disturbances, nervousness, dry mouth,
not controlled by other medications.
Mild itch or rash - see doctor promptly.
TABLE taken from: Epilepsy – A resource for teachers Written by Anne Little, Epilepsy Queensland Inc. 2002
MEDICATION CHART Page 2 MEDICATION TREATMENT POSSIBLE SIDE EFFECTS SECOND LINE DRUGS continued Vigabatrin
For the treatment of epilepsy previously
Drowsiness or sedation, fatigue, anxiety,
dizziness, headache, memory disturbances, double
particularly partial seizures. Considered
vision, unsteady gait, insomnia, irritability,
useful in treatment of infantile spasms.
weight gain, nausea, constipation, stomach pains. (Children - agitation, excitement, insomnia,
behavioural difficulties). Loss of peripheral vision -
should have visual field tests every 6 months. Topiramate
Fatigue, weight decrease, dizziness, confusion,
depression, agitation, hallucination, poor
coordination, speech disorder, kidney stones,
Tiagabine
Nausea, vomiting, diarrhoea, dizziness, tiredness,
headache, insomnia, poor concentration, loss of
Clonazepam
behaviour problems, excessive saliva, fatigue,
muscle weakness, vertigo, lightheadedness,
especially absences, myoclonic, tonic& tonic clonic, whether due to primaryor secondarily generalised epilepsy;but tolerance often develops. Diazepam
concentration, impaired memory and learning,
Primidone
Sedation, visual disturbances, nausea, headache,
and generalised epilepsy, however is noteffective in treating absence seizures. Oxcarbazepine
Tiredness, dizziness, headache, clumsiness,
agitation, blurred vision, nausea, lack of energy,
constipation, diarrhoea, abdominal pain. Levetiracetam
Somnolence, fatigue, coordination difficulties,
behavioural abnormalities, loss of strength,
Clobazam
concentration, impaired memory and learning,
TABLE taken from: Epilepsy – A resource for teachers Written by Anne Little, Epilepsy Queensland Inc. 2002
European Heart Journal Advance Access published November 29, 2006 The long-term value of sirolimus- and paclitaxel-elutingstents over bare metal stents in patients with diabetesmellitusJoost Daemen, Hector M. Garcia-Garcia, Neville Kukreja, Farshad Imani, Peter P.T. de Jaegere,Georgios Sianos, Ron T. van Domburg, and Patrick W. Serruys*Thoraxcenter, Erasmus Medical Center, Ba-583 Dr. Molewa
Bibliography, Göran Kronvall, MD, PhD Grubb, R., G. Kronvall, and L. Mårtensson . 1965. Some aspects of the relation between rheumatoid arthritis, anti gamma globulin factors and the polymorfism of human gamma globulin. Ann.N.Acad.Sci. 124 :865-872. Kronvall, G. 1965. Gm(f) activity of human gamma-globulin fragments. Vox Sanguis 10 :303-313. Kronvall, G. 1967. Ligand-binding si