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Curriculum Vitae

Nome: Nuno Lobo Antunes
Data de Nascimento: 10 de Maio de 1954
Nacionalidade: Portuguesa
Licença para praticar Medicina: 1977 Portugal
Educação:
Licenciado em Medicina, 1977
Faculdade de Medicina de Lisboa, Portugal (17 valores)
Treino post-graduado:
 Internato Policlínico, 1977-80. Hospitais Civis de Lisboa;  Estágio de Saúde Pública, 1981. Oliveira do Hospital;  Serviço Médico à Periferia, 1982. Manteigas;  Internato Complementar de Pediatria, 1982-85; 1988-89. Hospital Sta. Maria;  Neurology Residency, 1985-86 Neurological Institute of New York; Columbia University, New  Pediatric Neurology Residency, 1986-88. Neurological Institute of New York; Columbia Cargos e Títulos:
 Diretor Clínico do PIN – Progresso Infantil 2012 até ao presente;  Diretor Clínico do CADIn 2005 – 2012;  Presidente do Conselho de Administração da Fundação: Make-A-Wish 2008 – 2013;  Coordenador das áreas de Neurodesenvolvimento e Neurologia do CADin 2004 – 2012;  Coordenador da Unidade de Neuropediatria, Serviço de Pediatria Hospital de Santa Maria, 2001-  Assistente Hospitalar de Pediatria. Hospital de Santa Maria -1989 - 2004;  Consultor de Neurologia Pediátrica. IPO de Lisboa - 1993-95, 2001 - 2008  Membro do “Neurology steering Comitee”. Children Oncology Group. E.U.A. 1999-2000;  Representante português do Grupo de estudo “mioclonus-opsoclonus” da Sociedade Internacional de Oncologia Pediátrica (SIOP);  Neuro-oncology Fellow. Department of Neurology, Memorial Sloan-Kettering Cancer Center,  Assistant Attending Pediatric Neurologist. Departments of Pediatrics and Neurology Memorial Hospital for Cancer and Allied Diseases, New York, NY -1999-2001;  Assistant Attending Neurologist in Pediatrics. New York Presbyterian Hospital 1999-2001;  Assistant Professor of Neurology and Pediatrics. Cornell University Joan & Sanford I. Weill Sociedades Médicas e Cientificas:
 American Academy of Neurology;  Child Neurology Society;  Children Cancer Group;  Tri-State Pediatric Neurology Society;  Society for Neurooncology;  Sociedade Portuguesa de Neurologia;  Sociedade Portuguesa de Neurologia Pediátrica;  Sociedade Portuguesa de Pediatria;  Sociedade Portuguesa de Neurologia;  Academia Ibero-Americana de Neurologia Pediátrica;  Associação Portuguesa de Neuro-oncologia. Prémios:
 Pfizer para jovens investigadores: 1974 e 1976;  “Profissional do Ano” pela Rotary Clube Lisboa – Norte em 2013. Actividades de Investigação:
 Institute for the Study of Human Reproduction , com Peter W. Carmel, M.D. Columbia  Laboratório de Estudos de Linguagem do Centro de Estudos Egas Moniz com Dr. António Rosa  Neuro-immunology Laboratory - com Jerome Posner MD e Josep Dalmau MD Sloan-Kettering Revisor para as seguintes Revistas Internacionais:
 Epilepsia;  Pediatric Neurology;  Journal of Clinical Oncology;  Neurologia;  Cadernos de Saúde. Publicações:
A. Revistas Cientificas
1. A Damasio, A Castro-Caldas, E Calhau, J Grosso, J Ferro, N Lobo Antunes, H Damasio: Para
uma semiologia cerebral não-invasiva. J Sociedade Portuguesa de Ciências Médicas; 8,1975; 2. 2. A Castro Caldas, A Trindade, N Lobo Antunes, JM Ferro, JT Grosso, J Bravo Marques, A
Silveira Botelho: Valor dos estudos neuropsicológicos em tumores cerebrais. Revisão de 41 casos. J Sociedade Portuguesa de Ciências Médicas CXLI: 9, 1977; 3. A Castro Caldas, N Lobo Antunes, A Silveira Botelho, A Trindade, JT Grosso, JM Ferro, J
Bravo Marques, F Taborda: Localização anatómica das lesões responsáveis pelos diferentes padrões de resposta em audição dicótica. Análise Psicológica 2:489-94, 1979; 4. A Esaguy, N Lobo Antunes: Trombastenia de Glanzaman. Revista Portuguesa de Pediatria.14:
5. A Esaguy, M Chagas, M Figueira, N Lobo Antunes: Um estudo controlado de esteróides na
purpura idiopática trombocitopénica. Revista Portuguesa de Pediatria 15: 12-9, 1984; 6. JM Ferro, MD Esteves, N Lobo Antunes, JC Pimental: Demonstration of cerebellar involvement
in adrenoleukodystrophy. Neuroradiology 27: 185, 1985; 7. MJ Leal, N Lobo Antunes, V Martins, E J Roza Oliveira. Peritonite Biliar. Revista Portuguesa
8. J Costa, A Levy, I Menezes, C Barreto, M Cordeiro, N Lobo Antunes, MG Campos Andrade, N
Sanches, A Vaz Guedes, NM Levy: Convulsões neonatais. Revista Portuguesa de Pediatria 18: 385-97, 1987; 9. P Loio, M Batista, N Lobo Antunes, A Carvalho, M Correia, JS Sequeira. Choque hemorrágico e
encefalopatia . Revista Portuguesa de Pediatria 21: 265-268. 1990; 10. E Mendonca, N Lobo Antunes, M Correia, G Rodriges, A Carvalho, JS Sequeira: Síndroma de
Guillain-Barre . Revista Portuguesa de Pediatria 22, 1991; 11. IP Martins, JM Ferro, N Lobo Antunes: Le syndrome de Landau et Kleffner: evolution de
l’aphasie et resultat dun test decoute dichotique. Approache Neuropsychologique des Apprentissages Chez I'Enfant 1: 26-3 1, 1992; 12. N Lobo Antunes: Encefalites. Temas de Infecciologia Pediátrica, 1993;
13. I Martins, N Lobo Antunes, A Levy Gomes: Acquired visual agnosia in a child. Neuro-
psychological study. A.N.A.E.: 5:76-81,1993; 14. H Santos, I Cordeiro, A Medeira, E Mendonça, N Lobo Antunes, F Coelho Rosa:Schinzel-
Giedion syndrome. A clinical case with hypothyroidism and diabetes insipidus. Genetic Counselling, 1993; 15. IP Martins, N Lobo Antunes, A Castro Caldas, J Lobo Antunes: Atypical dominance for
language in developmental dysphasia. Dev Med Child Neurol 37: 85-90, 1995; 16. JP Vieira, N Lobo Antunes, A Levy Gomes: Infantile bilateral thalamic necrosis. Dev Med Child
17. N LoboAntunes,H Subramanian, LM DeAngelis: Brain abscesses in children with cancer. Med
18. N Lobo Antunes, LM DeAngelis: Neurological consultations in children with cancer. Ped
19. N Lobo Antunes, L Orne, T Small, P Szabolcs, F Boulad, E Lis. Posterior leukoencephalopathy
may not be reversible. Ped Neurol 20:241-243, 1999; 20. N Lobo Antunes. Consultas de urgencia en niños con cáncer sistémico. Rev Neurol 29(4):349-
21. N Lobo Antunes, M Souweidane, L Tavora. Globular tectal gliomas. Ped Neurol 21(1):492-495,
22. N Lobo Antunes, Y Khakoo, KK Matthay, RC Seeger, DO Stram, E Gerstner, LE Abrey, J
Dalmau. Antineuronal antibodies in patients with neuroblastoma and paraneoplastic opsoclonus-myoclonus. J Pediatr Hematol Oncol 22(4):315-20, 2000; 23. N Lobo Antunes. Acute neurologic complications in children with systemic cancer. J Child
24. Lobo Antunes N, Boulad F, Prasad V, Rosenblum M, Lis E, Souweidane M . Rolandic
encephalopathy and epilepsia partialis continua following bone marrow transplant. Bone Marrow Transplant 26(8): 917-9, 2000; 25. N Lobo Antunes, R Gorlick, E Calleja, E Lis. Numb chin syndrome in Ewing’s sarcoma. J
26. N Lobo Antunes, Lellouch-Tubiana, Chantal Kallifa, Olivier Delattre, Pierre-Khan, Marc
Rosenblum. Intracranial Ewing sarcoma-Peripheral Primitive Neuroectodermal Tumor of dural origin with molecular genetics confirmation. Journal of Neuro-oncology 51: 51-56, 2001; 27. E Rudnick, Y Khakoo, N Lobo Antunes, Robert C Seeger, Garrett M Brodeur, H Shimada,
Robert B Gerbing, Daniel O Stram, Katherine K Matthay. Opsoclonus-Myoclonus-Ataxia syndrome in Neuroblastoma: Clinical outcome and anti-neuronal antibodies. A children’s cancer group study. Medical and Pediatric Oncology. 36:612-622, 2001; 28. Ming X, Gonzales C, Burrowes D, Lastra C, N Lobo Antunes. Cavernous angioma of the
brainstem simulating diffuse pontine glioma. J Child Neurol 16: 614-15, 2001; 29. N Lobo Antunes. The spectrum of neurological disorders in children with cancer. Ped Neurol
30. N Lobo Antunes. Methotrexate toxicity presenting as Kluver-Bucy Syndrome. Ped Neurol
31. N Lobo Antunes. Radiation myelitis in a 5-year-old girl. J Child Neurol 17:217-9, 2002;
32. N Lobo Antunes. Mental status changes in children with cancer. Pediatr Neurol. 2002
33. N Lobo Antunes. Back and neck pain in children with cancer. Pediatr Neurol. 2002 Jul;27(1):46;
34. N Lobo Antunes. Seizures in children with systemic cancer. Pediatr Neurol. 2003
35. Begemann M, Lyden D, Rosenblum MK, Lis E, Wolden S, Antunes NL, Dunkel IJ. Primary
lepntomeningeal primitive neuroectodermal tumor. J Neurooncol. 2003 Jul;63(3):299-303; 36. Begemann M, Trippett TM, Lis E, Antunes NL. Brain metastases in hepatoblastoma. Pediatr
37. Gilheeney SW, Lyden DC, Sgouros S, Antunes N, Gerald W, Kramer K, Lis E, Meyers P, Rosen
N, Thaler HT, Trippett T, Wexler L, Dunkel IJ. A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies. Pediatr Blood Cancer. 2006 Sep 13; 38. Simultaneous occurrence of neurofibromatosis and tuberous sclerosis, acquired as neo-
mutations. Janeiro PC, Cunha MS, Cordeiro I, Santos HG, Antunes NL. Rev Neurol. 2008 Mar 16-31;46(6):347-50. B. Abstracts:
1. T Paiva, A Atalaia, F Pinto, N Lobo Antunes, J Fernandes: Arousal in nocturnal paroxysmal
dystonia and nocturnal crisis. Epilepsia 34: supp 2, 1993; 2. L Albuquerque, J Pimentel, L Tavora, N Lobo Antunes: Immunohistochemical study of
proliferative indexes in childhood medulloblastomas. J Neuro-Onc 24:1233, 1995; 3. N Lobo Antunes,H Subramanian, LM DeAngelis: Brain abscesses in children with cancer. Ann
4. N Lobo Antunes, J Johnson Jr, LM DeAngelis: The spectrum of neurologic disease in children
5. N Lobo Antunes,Y Khakoo, DO Stram, RC Seeger, KK Mathay, J Dalmau: Antineuronal
antibodies in patients with neuroblastoma and paraneoplastic opsoclonus-myoclonus. Ann Neurol 42:534, 1997; 6. N Lobo Antunes: Mutism after posterior fossa surgery: A behavioral syndrome. Child’s Nerv
7. S Acharya, N Lobo Antunes, J Finlay, B Kushner, P Meyers, N Wollner: Intracranial metastases
in pediatric solid tumors. Child’s Nerv Syst 14:521, 1998; 8. MH Geffner, R Trifiletti, A Aledo, N Lobo Antunes. Bilateral dilated pupils as a presentation of
leptomeningeal disease. Child’s Nerv Syst 14:524, 1998; 9. N Lobo Antunes, L Orne, T Small, P Szabolcs, F Boulad, E Lis. Encephalomalacia due to
“reversible” posterior leukoencephalopathy. Proceedings of the 5th International Conference on long term complications of treatment of children and adolescents with cancer. Niagara-on-the-Lake, June 19-20, 1998; 10. AI Lopes, N Lobo Antunes, M J Melo, A Batista, M Misrahi. Wilson’s disease in childhood - a
case of early onset with molecular study. J Hepatol. Suppl 1,28:229, 1998; 11. N Lobo Antunes, M Bell, E Lis, F Boulad, P Steinherz. Stroke associated with stomatococcus
muciliginosus meningitis and aeromonas hydrophila sepsis. Proceedings of VII Annual Meeting of Iberoamerican Academy of Pediatric Neurology, Cartagena de Indias, Colombia, April 26-28, 1999; 12. N Lobo Antunes, S Chi, L Butros, F Boulad, V Prasad, J Damore, E Lis, G Solomon, P
Steinherz. Two cases of myoclonus in children with cancer. Proceedings of VII Annual Meeting of Iberoamerican Academy of Pediatric Neurology, Cartagena de Indias, Colombia, April 26-28, 1999; 13. N Lobo Antunes, A Pierre-Khan, O Dellatre, C. Kalifa, A Lellouch Tubiana, M Rosenblum.
Primary peripheral primitive neuroectodermal tumor/Ewing’s sarcoma of the leptomeninges. Annals of Neurology, 46(3):550, 1999; 14. N Lobo Antunes. Headache in children with cancer. Neuro-Oncology, 1:4: 296, 1999;
15. N Lobo Antunes. Iatrogenic neurologic disease in children with cancer. Neuro- Oncology, 1 (4):
16. N Lobo Antunes. Movement disorders in children with cancer. Proceedings of VIIth Annual
Meeting of Iberoamerican Academy of Pediatric Neurology, Miami, May 24-27, 2000; 17. Kramer K, Cheung NKV, Humm J, Dantis E, Finn R, Yeh S, Antunes NL, Dunkel IJ,
Souwedaine M, Larson S. Radioimmunotherapy (RIT) of GD2-positive Leptomeningeal (LM) Cancer using 131-I-3F8: Patient Imaging and Dosimetry. Proceedings of the 9th International symposium on pediatric neuro-oncology, San Francisco, CA, June 2000; 18. N Lobo Antunes. Back and neck pain in children with systemic cancer. Neuro-Oncology, Suppl
19. N Lobo Antunes, I Dunkel, P Steinherz, E Lis. Radiation-induced cavernous angiomas of the
brain. Neuro-Oncology, Suppl 1,2:S71, 2000; 20. N Lobo Antunes. Mental status changes in children with cancer. Annals of Neurology 48(3):
21. I. Dunkel, S. Sgouros, N Lobo Antunes, K. Kramer, B. Kushner, E. Lis, D. Lyden, P. Meyers, N.
Rosen, T. Trippett. A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies: Preliminary results. Proceedings of ASCO 20: 375a, 2001; 22. Teresa Bagulho, N Lobo Antunes, Jeffrey Allen, Jonathan Finlay. The neurologic features of
high grade gliomas in children: A report of the Children’s Cancer Group CCG-945 Study. Proceedings of the 14th International Conference on Brain Tumor Research and Therapy Asheville, North Carolina, May 2001; 23. Ira Dunkel, N Lobo Antunes. A pilot trial of reduced volume boost via intensity modulated
radiation therapy (IMRT) with craniospinal radiation therapy (RT) and chemotherapy for patients with newly diagnosed medulloblastoma. Proceedings of the SIOP 2002 Congress. Porto 2002; 24. N Lobo Antunes; Leitão, I; Alves, M; Macedo, J. Asperger's Syndrome: A Preliminary Study of
a New Questionnaire. Social Brain 2. Glasgow 2006; 25. N Lobo Antunes; Alves, M; Filipe C. An innovative center for children with developmental
disabilities. Social Brain 2. Glasgow 2006. C. Capítulos:
1. “Complications of Pediatric Cancer” in: Cancer Neurology: A guide to clinical management.
David Schiff and Patrick Wen (Editors). Humana Press (in press).
D. Livros:
1. Em Nome do Pai – 2013;
2. Vida em Mim – 2011;
3. Mal Entendidos – 2009;
4. Sinto Muito – 2008.
E. Apresentações (platform presentations) e Conferências no estrangeiro:
1. “Dichotic Listening and Aphasia,” IInd Iberian-American Congress of Neurology, Barcelona,
2. “Seizure Disorders”. The Neurologically Impaired Neonate. Columbia-Presbyterian Medical
Center Regional Perinatal Network, New York, USA. Abril 1988; 3. “Diagnostic Tools and Prognostic Indicators”. The Neurologically Impaired Neonate. Columbia-
Presbyterian Medical Center Regional Perinatal Network, New York, USA. Abril 1988; 4. “Nine Cases of SSPE Following a Measles Epidemic in the Lisbon Metropolitan Area,” IVth
Congress of the European Pediatric Neurology Society. Paris, França 1990; 5. “ Epilepsia” Hospital Agostinho Neto. Cidade da Praia, Cabo Verde. 1993;
6. “Coma” Idem;
7. “Traumatismos cranianos” Idem;
8. “Another Case of L-2-OH. Glutaric Aciduria of Mediterranean Origin,” Clinical Applications of
Mass Spectometry, Institute of Child Health. London, Inglaterra. 1993; 9. “Acute Parainfectious Encephalopathies,” Meeting of Spanish Society of Pediatric Neurology.
10. “Controversies in the Treatment of Pediatric Brain Tumors,” Neurosurgery Grand Rounds.
University of Medicine and Dentistry of New Jersey, Newark. Setembro 1996; 11. “Controversies in the Treatment of Pediatric Brain Tumors” Neurology Grand Rounds. New
York Hospital, Cornell University. New York, NY. Outubro 1997; 12. “Current Treatment of Pediatric Brain Tumors” Pediatric Neurology Grand Rounds. University
of Medicine and Dentistry of New Jersey, Newark. Novembro 1997; 13. “Controversies in the Treatment of Pediatric Brain Tumors” Pediatric Grand Rounds. Memorial
Sloan-Kettering Cancer Center. New York, NY. Janeiro 1998; 14. “Treatment of Pediatric Brain Tumors” International Course of Neuro-oncology, Albert Einstein
Hospital. Sao Paulo, Brasil. Março 1998; 15. “Cerebral Metastases in Children” International Course of Neuro-oncology, Albert Einstein
Hospital. Sao Paulo, Brasil. Março 1998; 16. “Neurologic Complications of Cancer in Children,” International Course of Neuro-oncology,
Albert Einstein Hospital. Sao Paulo, Brazil. Março 1998; 17. “Treatment of Pediatric Brain Tumors,” Pediatric Neurology Grand Rounds. University of
Medicine and Dentistry of New Jersey, Newark. Setembro 1998; 18. “Controversies in the Treatment of Pediatric Brain Tumors” Pediatric Grand Rounds. Lincoln
19. “The Treatment of Pediatric Brain Tumors an Overview “ Neurology Grand Rounds. JFK
Neuroscience Institute. Edison, NJ. Novembro 1998; 20. “Common Neurologic Complications in Children with Cancer” Pediatric Neurology Grand
Rounds. Columbia-Presbyterian Medical Center. New York, NY. Março 1999; 21. “Neurological Complications of Children with Cancer” Pediatric Grand Rounds. Memorial
Sloan-Kettering Cancer Center. New York, NY. Setembro 1999; 22. “Treatment of Pediatric Brain Tumors: An Overview” Pediatric Grand Rounds. New York
Presbyterian Hospital. New York, NY. Outubro 1999; 23. “Neurological Complications of Pediatric Cancers” Neurology Grand Rounds. New Jersey
Neuroscience Institute at JFK Medical Center. Edison, New Jersey. Dezembro 1999; 24. Neurological Complications of Pediatric Cancers. Conferência produzida no Porto Novembro
2003, 31a reunião anual da Societé Européenne de Neurologie Pédiatrique; 25. ECIS International Meeting , Madrid 2007: Biological Basis of Learning difficulties;
26. ECIS International Meeting , Madrid 2007: PHDA;
27. ECIS International Meeting , Madrid 2007: Asperger Syndrome;
28. ECIS International Meeting , Nice 2008: Biological Basis of Learning difficulties;
29. ECIS International Meeting , Nice 2008: PHDA;
30. ECIS International Meeting , Nice 2008: Asperger Syndrome.

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