Dr Frances Pitsilis – 2A Dodson Avenue, Milford, Auckland PO Box 31-572, Milford, North Shore City 0741, New Zealand
PHONE: +64 9 486 0030 FAX: +64 9 486 0333 EMAIL: [email protected] WEBSITE: www.drfrances.co.nz
TOO MUCH OF A GOOD THING?
As the warm weather and summer approaches and we are all looking forward to getting more sunshine, feeling a
bit brighter that the better weather brings, we must also be aware of the dangers as well as the benefi ts of sun
exposure. Sun exposure can be managed in a way that is benefi cial and safe, and prevents health problems like
skin cancers and excessive ageing of the skin.
Until the 1920s, people ensured that they avoided the sun because a tan meant that you worked outside. However,
legend has it that Coco Chanel, the great French designer, fi rst popularised the idea of the suntan after she
accidentally sunburned whilst on a boat in the 1920s. From this era onwards, people started looking for a suntan
because it showed that they could afford to travel. Dangers of excessive sun exposure Skin ageing – signs and problems:
As the body ages there will be ageing signs in the skin, however, when there is excessive sun exposure these signs
are accelerated. Photo ageing is due to damage caused by short wavelength ultraviolet radiation (UVB) injury to
the epidermis. Longer wavelength ultraviolet radiation (UVA) damages the middle layers or dermis and any infrared
A radiation damages the deeper dermis and subcutaneous tissue. When the skin is excessively exposed to the sun
without protection these ageing changes become apparent sooner and tend to occur on sun exposed areas like the
face, neck, upper chest, backs of hands and arms.
People who are fair skinned have more problems than those who are darker skinned.
Solar elastosis is a photoageing change in the skin which really just refers to the thinning and stretching of the
support tissues in the dermis, as well as predictable changes in appearance that will be described below.
Fine lines and wrinkles can occur on the skin, especially around the mouth. As the epidermis becomes thinner due
to reduction in oestrogen in women, these fi ne lines become more predominant.
The skin gets thinner and so veins and blood vessels can be seen more easily.
Pigmentation change can occur all over the more exposed areas and so, in fair skinned people, can result in
numerous freckles. In anyone there can be change of brown and red discolouration of the neck and upper chest,
which is caused poikiloderma. Brown blotches, called solar lentigos, are mainly on the face and arms. Guttate hypomelanosis is a change due to ageing where there are patches of white as the skin becomes tanned
– this is because the white areas have lost their pigment with age (this are not really caused by excessive sun
exposure, but are included for completeness).
Excessive blood vessel production can be caused by ageing and/or sun exposure. The most common are
telangiectasias which are shown as red veins and fl ushes of red, mostly on the cheeks and nose.
Other ageing skin lesions include solar comedones which are milia-like lesions that sprout up anywhere on
excessively sun exposed skin. Colloid milia can also occur.
Progressing a little bit further, solar keratoses, or otherwise known as actinic keratoses, are the result of sun
damage that causes the epithelium to overgrow and become heaped up. These lesions are precancerous and tend
to occur on bald heads, tips of ears, faces, arms and any sun exposed areas. They can be multiple, fl at, thickened,
scaly, warty, skin coloured or even a bit reddened. Sometimes a keratoses can develop into a horn-like growth.
Treatments Treatment of brown or red pigmented lesions can be performed with intense pulsed light. Intense pulsed light will
also get some of the veins. Vascular laser can treat the rest of the veins.
Milia can be treated with extraction, liquid nitrogen treatment, and to some degree, microdermabrasion.
If solar keratoses are treated early (often simply with liquid nitrogen application by the family doctor or nurse) then
skin cancer can be avoided. If they are not treated then skin cancer may develop in up to 25% of cases. Skin Cancers Skin cancer is the ultimate sun damage that the skin experiences and there are three main types: Basal cell carcinoma mostly tends to occur around the face but can also occur on other parts of the body. It has
a particular signature appearance with a pearly rounded edge that contains small blood vessels. Squamous cell carcinoma often grows out of actinic or solar keratoses and can occur anywhere. Of particular
worry is when squamous cell carcinoma occurs on the lip, earlobe or even on the scalp – this is because these can
Malignant melanoma is the most worrying of the skin cancers and is the one that looks dark. It is very rare to
have an amelanotic malignant melanoma (devoid of pigment).
The three groups of people who are most at risk of malignant melanoma are:
2. Those with a family history of malignant melanoma.
3. Those who have dysplastic naevus syndrome – this is a condition whereby the person has more than around
20 moles that look different sizes, shapes and colours. In this condition, most of these moles occur on the
What are the risks of malignant melanoma in New Zealand? A survey in New Zealand has shown the following statistics:
• Fewer than 1% occurred in those under 20.
• 13% occurred in people 20-40 years old.
• 36% occurred in those aged 40-59.
• 51% occurred in those aged over 60.
It appears that older people are getting malignant melanoma more because they are the generation that did not
know about excessive sun risk in their youth. What increases your risk of melanoma apart from the three conditions mentioned, include the following:
• How much sun exposure occurred during childhood.
• Amount of sunburn during life but especially during childhood.
Malignant melanoma grows from the melanocytes in the skin which give skin its pigment. The melanocytes
are there to produce melanin which protects the skin by absorbing ultraviolet radiation. In effect, a tan results
from damage to the skin, and to the melanocytes by UV radiation. When melanocytes overgrow uncontrollably,
PO Box 31-572, Milford, North Shore City 0741, New Zealand
PHONE: +64 9 486 0030 FAX: +64 9 486 0333
EMAIL: [email protected] WEBSITE: www.drfrances.co.nz
It is very important to catch malignant melanoma as early as possible because this increases survival. The signs to look for are:
a Any change in the area of a pre-existing mole.
b Any change in the border or outline of an existing mole.
c Any change in the colour or colour distribution of an existing mole.
d Any change in the diameter of an existing mole.
I always say to people that they should look for two main things because they will never remember the a, b c and
d – and that is to have any new mole checked or any change in an existing mole checked.
With all of these skin cancers, it is important not to read this article and presume that you know what to look for. It
is very important to have any change in any mole or any new mole checked by a doctor.
Sunblocks and skin care are important in helping us to manage our sun exposure safely and benefi cially. Sunscreens Sun screens work by either absorbing the UV or refl ecting it. Titanium and zinc work by refl ecting the radiation that
lands on the surface of the skin. Chemical absorbers include oxybenzone.
Neither titanium dioxide nor oxybenzone can quite get the whole of the sun spectrum, however, zinc can and this is
why I prefer zinc based sunblockers.
However, one company has added a molecule to oxybenzone and has been able to create a chemical blocker that
covers the whole of the sun spectrum.
It is important to apply sunblock at least 20mins before going out into the sun because it takes this long for it to
work. When sunbathing, it is important to reapply sunblock frequently, especially after swimming. The SPF rating is
not useful if the sunblock can be rubbed off or washed off with swimming.
When considering going out into the sun, it is best to avoid the high UV times between 11am and 4pm. After that,
the next most effective protection is covering up and then the last most effective protection is using a sunscreen.
Skin care that protects and reverses sun damage:
Retinoids come up again and again. These are molecules derived from vitamin A like retinol, retinylpalmitate and
tretinoin. They are a multi benefi cial group of skin treatment that not only reduce wrinkles by communicating
with the DNA of skin cells and ordering the skin cells to behave normally but also have other benefi ts. The other
benefi ts include protecting the skin from UV and assisting in wound healing. As you know, retinoids are frequently
used in acne and rosacea, as well as in cosmetic treatments. Antioxidant vitamins protect and to some degree can restore sun damaged skin. To different degrees the following ingredients of skin care have been found to do this.
Natural substances that are antioxidant include green tea and pycnogenol. Vitamin D Having expressed concern about over exposure to the sun and the damage and serious risks that can occur, it
is important to have balance about sun exposure. This is because we have now gone too far in some situations
and we now know that there is a worldwide epidemic of vitamin D defi ciency. It is estimated that 50% of the
population is vitamin D defi cient. Have we taken the message of staying out of the sun, covering up and applying
PO Box 31-572, Milford, North Shore City 0741, New Zealand
PHONE: +64 9 486 0030 FAX: +64 9 486 0333
EMAIL: [email protected] WEBSITE: www.drfrances.co.nz
There are numerous benefi ts of vitamin D that many of us are now not able to access because we work indoors
and become vitamin D defi cient to start with, and then we actively avoid the sun.
By far the biggest source of vitamin D is the sun. There is a precursor molecule in the skin which when exposed
to the sun, makes an early form of vitamin D which then goes to the liver and is converted to 25-hydroxy vitamin
D. This then goes to the kidney, which then makes the fi nal molecule dihydroxy vitamin D. Vitamin D is not only
important for bone health but it affects every cell in the body. Health effects include helping you lose weight
by improving insulin and glucose management in the body, reduction of heart disease and diabetes prevention,
reduction of cancer, improvement of the immune system & multiple sclerosis and many more health benefi ts. Normalising vitamin D levels can improve many conditions like:
• All cancers combined by up to 75%.
There are signs that our population is vitamin D defi cient because studies in New Zealand have shown us that
in one Wellington clinic, up to 83% of pregnant women were vitamin D defi cient, as we are also now starting to
see cases of rickets in children in New Zealand – this is the condition where the bones of children don’t develop
normally because of lack of vitamin D.
I have observed one other interesting trend. I have noticed that the melanoma incidence of Australia and New
Zealand has been increasing since we started introducing sun protection - at the same time we have developed a
tendency to vitamin D defi ciency. As vitamin D can prevent cancer, it is easy to wonder whether this association
of high melanoma with excessive sunblock use and sun avoidance could be due to this. However, no research has
been done to try and show this association.
So, where do we go from here? Well, it is all about moderation. I believe it is okay to enjoy some sunshine on your
body but make sure that you put sunblock on the most exposed places like face, neck, décolletage and backs of
hands and arms. Never allow yourself or your children to get burnt.
If you are worried about lack of vitamin D from the sun, you can get it in your diet by taking cod liver oil and
having plenty of oily fi sh like salmon, herring and sardines. If your vitamin D level is low, there is good news
because you can take it as a tablet – your family doctor can test you.
It is always best to enjoy the sun safely. Behaving in moderation so that you get enough vitamin D but don’t age
and damage your skin requires commonsense and good management. You can always take a vitamin D tablet and/
PO Box 31-572, Milford, North Shore City 0741, New Zealand
PHONE: +64 9 486 0030 FAX: +64 9 486 0333
EMAIL: [email protected] WEBSITE: www.drfrances.co.nz
20 septembre 2008 Liste des interdictions 2009 de l’AMA Résumé des principales modifications et clarifications PARAGRAPHE D’INTRODUCTION • L’article 4.2.2 du Code 2009 établit qu’« Aux fins de l’application de l’article 10 (Sanctions à l’encontre des individus), toutes les substances interdites sont des « substances spécifiées », sa
Carrie Pearson The Coalition for Science After School <[email protected]> on behalf of The Coalition for Science After School <[email protected]> Subject: Categories: Is this email not displaying correctly? View it in your browser. January 2013 "Life is not divided into semesters. You don't get summers off and very few employer